NOMO1 (NM_014287) Human Untagged Clone
$1,065.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | NOMO1 |
| Synonyms | Nomo; PM5 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_014287 |
| Insert Size | 4230 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_014287.3, NP_055102.3 |
| RefSeq Size | 4261 bp |
| RefSeq ORF | 3669 bp |
| Locus ID | 23420 |
| UniProt ID | Q15155 |
| Cytogenetics | 16p13.11 |
| Summary | This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). provided by RefSeq, Jul 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_014287" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC211944 | NOMO1 (Myc-DDK-tagged)-Human NODAL modulator 1 (NOMO1) | 10 ug |
$1,064.00
|
|
| RC211944L1 | Lenti ORF clone of Human NODAL modulator 1 (NOMO1), Myc-DDK-tagged | 10 ug |
$1,364.00
|
|
| RC211944L2 | Lenti ORF clone of Human NODAL modulator 1 (NOMO1), mGFP tagged | 10 ug |
$1,364.00
|
|
| RC211944L3 | Lenti ORF clone of Human NODAL modulator 1 (NOMO1), Myc-DDK-tagged | 10 ug |
$1,364.00
|
|
| RC211944L4 | Lenti ORF clone of Human NODAL modulator 1 (NOMO1), mGFP tagged | 10 ug |
$1,364.00
|
|
| RG211944 | NOMO1 (tGFP-tagged) - Human NODAL modulator 1 (NOMO1) | 10 ug |
$1,264.00
|
|
Citations
Low oxygen levels induce the expression of the embryonic morphogen Nodal
Quail, Taylor, Walsh et al
Mol. Biol. Cell (2011) 22 (24), 4809-21 DOI: 10.1091/mbc.E11-03-0263
Quail, Taylor, Walsh et al
Mol. Biol. Cell (2011) 22 (24), 4809-21 DOI: 10.1091/mbc.E11-03-0263
Cited by 11
AI Summary: OriGene products contributed to this study by providing HIF-1α and HIF-2α shRNA constructs, which were used to knock down these proteins and investigate their roles in the oxygen-mediated regulation of Nodal expression.
Snippet: 1 and HIF-2 in the O 2 -mediated regulation of Nodal. We first examined the consequences of knocking down HIF-1α and/or HIF-2α in C81-61 and T47D cells. Western blot analyses confirmed that HIF-1α and HIF-2α protein
Showing 1-1 of 1 papers.
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