C11orf73 (HIKESHI) (NM_016401) Human Untagged Clone
SKU
SC114286
C11orf73 (untagged)-Human chromosome 11 open reading frame 73 (C11orf73), transcript variant 1
$300.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | C11orf73 |
| Synonyms | C11orf73; HLD13; HSPC138; HSPC179; L7RN6; OPI10 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_016401 |
| Insert Size | 800 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_016401.2, NP_057485.2 |
| RefSeq Size | 1152 bp |
| RefSeq ORF | 594 bp |
| Locus ID | 51501 |
| UniProt ID | Q53FT3 |
| Cytogenetics | 11q14.2 |
| Summary | This gene encodes an evolutionarily conserved nuclear transport receptor that mediates heat-shock-induced nuclear import of 70 kDa heat-shock proteins (Hsp70s) through interactions with FG-nucleoporins. The protein mediates transport of the ATP form but not the ADP form of Hsp70 proteins under conditions of heat shock stress. Structural analyses demonstrate that the protein forms an asymmetric homodimer and that the N-terminal domain consists of a jelly-roll/beta-sandwich fold structure that contains hydrophobic pockets involved in FG-nucleoporin recognition. Reduction of RNA expression levels in HeLa cells using small interfering RNAs results in inhibition of heat shock-induced nuclear accumulation of Hsp70s, indicating a role for this gene in regulation of Hsp70 nuclear import during heat shock stress. provided by RefSeq, Apr 2016 |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
"NM_016401" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC200866 | C11orf73 (Myc-DDK-tagged)-Human chromosome 11 open reading frame 73 (C11orf73), transcript variant 1 | 10 ug |
$300.00
|
|
| RC200866L3 | Lenti ORF clone of Human chromosome 11 open reading frame 73 (C11orf73), transcript variant 1, Myc-DDK-tagged | 10 ug |
$600.00
|
|
| RC200866L4 | Lenti ORF clone of Human chromosome 11 open reading frame 73 (C11orf73), transcript variant 1, mGFP tagged | 10 ug |
$600.00
|
|
| RG200866 | C11orf73 (tGFP-tagged) - Human chromosome 11 open reading frame 73 (C11orf73), transcript variant 1 | 10 ug |
$489.00
$500.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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