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PAK6 (NM_020168) Human Untagged Clone

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SKU
SC113203
PAK6 (untagged)-Human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1
  $625.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol PAK6
Synonyms PAK5
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC113203 sequence for NM_020168 edited (data generated by NextGen Sequencing)
ATGTTCCGCAAGAAAAAGAAGAAACGCCCTGAGATCTCAGCGCCACAGAACTTCCAGCAC
CGTGTCCACACCTCCTTCGACCCCAAAGAAGGCAAGTTTGTGGGCCTCCCCCCACAATGG
CAGAACATCCTGGACACACTGCGGCGCCCCAAGCCCGTGGTGGACCCTTCGCGAATCACA
CGGGTGCAGCTCCAGCCCATGAAGACAGTGGTGCGGGGCAGCGCGATGCCTGTGGATGGC
TACATCTCAGGGCTGCTCAACGACATCCAGAAGTTGTCAGTCATCAGCTCCAACACCCTG
CGTGGCCGCAGCCCCACCAGCCGGCGGCGGGCACAGTCCCTGGGGCTGCTGGGGGATGAG
CACTGGGCCACCGACCCAGACATGTACCTCCAGAGCCCCCAGTCTGAGCGCACTGACCCC
CACGGCCTCTACCTCAGCTGCAACGGGGGCACACCAGCAGGCCACAAGCAGATGCCGTGG
CCCGAGCCACAGAGCCCACGGGTCCTGCCCAATGGGCTGGCTGCAAAGGCACAGTCCCTG
GGCCCCGCCGAGTTTCAGGGTGCCTCGCAGCGCTGTCTGCAGCTGGGTGCCTGCCTGCAG
AGCTCCCCACCAGGAGCCTCGCCCCCCACGGGCACCAATAGGCATGGAATGAAGGCTGCC
AAGCATGGCTCTGAGGAGGCCCGGCCACAGTCCTGCCTGGTGGGCTCAGCCACAGGCAGG
CCAGGTGGGGAAGGCAGCCCTAGCCCTAAGACCCGGGAGAGCAGCCTGAAGCGCAGGCTA
TTCCGAAGCATGTTCCTGTCCACTGCTGCCACAGCCCCTCCAAGCAGCAGCAAGCCAGGC
CCTCCACCACAGAGCAAGCCCAACTCCTCTTTCCGACCGCCGCAGAAAGACAACCCCCCA
AGCCTGGTGGCCAAGGCCCAGTCCTTGCCCTCGGACCAGCCGGTGGGGACCTTCAGCCCT
CTGACCACTTCGGATACCAGCAGCCCCCAGAAGTCCCTCCGCACAGCCCCGGCCACAGGC
CAGCTTCCAGGCCGGTCTTCCCCAGCGGGATCCCCCCGCACCTGGCACGCCCAGATCAGC
ACCAGCAACCTGTACCTGCCCCAGGACCCCACGGTTGCCAAGGGTGCCCTGGCTGGTGAG
GACACAGGTGTTGTGACACATGAGCAGTTCAAGGCTGCGCTCAGGATGGTGGTGGACCAG
GGTGACCCCCGGCTGCTGCTGGACAGCTACGTGAAGATTGGCGAGGGCTCCACCGGCATC
GTCTGCTTGGCCCGGGAGAAGCACTCGGGCCGCCAGGTGGCCGTCAAGATGATGGACCTC
AGGAAGCAGCAGCGCAGGGAGCTGCTCTTCAACGAGGTGGTGATCATGCGGGACTACCAG
CACTTCAACGTGGTGGAGATGTACAAGAGCTACCTGGTGGGCGAGGAGCTGTGGGTGCTC
ATGGAGTTCCTGCAGGGAGGAGCCCTCACAGACATCGTCTCCCAAGTCAGGCTGAATGAG
GAGCAGATTGCCACTGTGTGTGAGGCTGTGCTGCAGGCCCTGGCCTACCTGCATGCTCAG
GGTGTCATCCACCGGGACATCAAGAGTGACTCCATCCTGCTGACCCTCGATGGCAGGGTG
AAGCTCTCGGACTTCGGATTCTGTGCTCAGATCAGCAAAGACGTCCCTAAGAGGAAGTCC
CTGGTGGGAACCCCCTACTGGATGGCTCCTGAAGTGATCTCCAGGTCTTTGTATGCCACT
GAGGTGGATATCTGGTCTCTGGGCATCATGGTGATTGAGATGGTAGATGGGGAGCCACCG
TACTTCAGTGACTCCCCAGTGCAAGCCATGAAGAGGCTCCGGGACAGCCCCCCACCCAAG
CTGAAAAACTCTCACAAGGTCTCCCCAGTGCTGCGAGACTTCCTGGAGCGGATGCTGGTG
CGGGACCCCCAAGAGAGAGCCACAGCCCAGGAGCTCCTAGACCACCCCTTCCTGCTGCAG
ACAGGGCTACCTGAGTGCCTGGTGCCCCTGATCCAGCTCTACCGAAAGCAGACCTCCACC
TGCTGA

Clone variation with respect to NM_020168.4
249 g=>a
5' Read Nucleotide Sequence
>OriGene 5' read for NM_020168 unedited
CACATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCATCTGATTATTT
TGGGAGCTGGAAACTTGGAGCTGCACCTGAGTCCCGCCCCTTCTAGCTCTCCCCTCCCTA
CCTTGGGCTCCAGGAAGATGGGACTTGCTGTGAGTCTGCTGCCACCCCCTAAAGATATGG
AAGACGCTGTGGGGGCCAGAAGTGCCCGGGGGGCTGTGGCAGCAGGCAGAGTGCAATAGC
AGATATGGTGGTCAGGCTGCCCGTGTGTGTCCTCTGGAGGTGTTGGGACAGAAGGGCAGT
CTTGTCCGAGCTGACTGGAGTCCTCCCGGGCTGGCTCTGAACTCATCTCCCACGGGGATG
TTTCGGTAAAGGAGTGGCTTCTGGGGTCGGAGTGGCATTTGGAGAGCGAGGCTGGATTGG
CTTANGCTGGCCTGGGCAGGGAGTGCCGCTTCCTGGGCTAGAGACAAGCACCAGCCTGCA
GTGGAGAACGCAGGACCCCGCTGCCCAGAAGGAGCAGCCACGGCCTGCGGAGGACTGGCC
CAGCAAGGTCCCAGGTCTTCCCTCTCCTCAGCGCCTAAGAGAGAGGCCCAGTGCGGGTGA
GGAGTCGCGAGGAAGAGGCGGAAGGCGCCGGAAGGCACCATGTTCCGCAAGAAAAAGAAG
AAACGCCCTGAGATCTCAGCGCCACAGAACTTCCAGCACCGTGTCCACACCTCCTTCGAC
CCCAAAGAAGGCAAGTTTGTGGGCCTCCCCCCACAATGGCAGAACATCCTGGACACACTG
CGGCGCCCCAAGCCGTGGTGGACCCTTCGCGATCACACGGGTGCAGCTCCAGCCCATGAA
GACAGTGGTGCGGNGCANCGCGATGCCTGTGGATGGCTACATCTCAGGGCTGCTCACGAC
TNCCAGAAGTGTCAGTCATCAGCTCACACCCTGCGTGGCCGCAGC
3' Read Nucleotide Sequence
>OriGene 3' read for NM_020168 unedited
NTTTTTTGACTCTGCCCCGGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTTT
TGGCTTTGAACACTCAATTTAATTTAAAACAGGCACAAGTGCAAACAATTCACAAAAATT
TCTAGGGAAGATGCTTTTGTTTTGAAAACTCTGACCCTTAAAAAAAAGTCCTTGCAATTT
CTTTGCCCCCAGGTAGGTCACTAGGGAGCAGAAGAATCTAAAAATATTATCTAGATAGAA
AGGGTCCAGACACCTGAAGTTCTTTCCTGGAATTCCATCTCACAGCAGCCCTGAAGTGGG
GCAGGGCCGAGGAGGACAAGGAGACAGCAGTCTGTGGAGGCAGCTGGGGCAGATGGTTTG
CACACATGGATGCCTGTGACCTTGACATGATGGAAACCCGGAGGTGGTTCGCCTTCTCTC
CCAGATAGGGTTCTGAAGAGAACAATGGGTCCCTGATGACCTGGCTATTGAGATAAACTT
GACAGGTAACACAGCCGCCAATCCTTACATTCCTGTCTCTGGCCCTCACGATGCACAGTA
CAGGAGAAGCTCAAAACCCTCCTGAGCCTCCAGGAGTGCTAGACTTACCATGGACCACTC
CACTGGCCACGTACACACCGGAGTGGCAGAGGCGGCAACCCCGCTCAACAAAGCCGGTTC
CTTTATGCCAATACTTATTGGCCAAAACGGGCCCTTCTCTCCGAAACCGGTTGCGGGCGA
CCCTGCAGAGACCCGGGTTGTTTTGGGGGGTTTTCTTTCCCTTACAGCTCTTTACTACCC
CCCCACCCCCCCCTACCTTGTCTCTCTTTTCGCAACCGCCCACCCCTTTTCCCCCCCTCC
CTCTCCTTCCCCCTCTCCCCAAAATGCGCCCCCCCTCCCCTCCCTCCCCTCCCTTCCTGT
CTTCTCCCCCCCCACCCCCGCCG
Restriction Sites NotI-NotI |
ACCN NM_020168
Insert Size 4470 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_020168.3, NP_064553.1
RefSeq Size 3889 bp
RefSeq ORF 2046 bp
Locus ID 56924
UniProt ID Q9NQU5
Cytogenetics 15q15.1
Domains PBD, pkinase, S_TKc, TyrKc
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Axon guidance, ErbB signaling pathway, Focal adhesion, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway
Summary This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2015
Transcript Variant: This variant (1) encodes isoform 1. Variants 1 and 4 encode the same isoform (1).
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Documents
Resources
"NM_020168" in other vectors (7)
SKU Description Size Price
RC207438 PAK6 (Myc-DDK-tagged)-Human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1 10 ug
$624.00
RC207438L1 Lenti ORF clone of Human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1, Myc-DDK-tagged 10 ug
$924.00
RC207438L2 Lenti ORF clone of Human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1, mGFP tagged 10 ug
$924.00
RC207438L3 Lenti ORF clone of Human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1, Myc-DDK-tagged 10 ug
$924.00
RC207438L4 Lenti ORF clone of Human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1, mGFP tagged 10 ug
$924.00
RG207438 PAK6 (tGFP-tagged) - Human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1 10 ug
$789.00 $824.00
SC323578 PAK6 (untagged)-Kinase deficient mutant (K436M) of Human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1 10 ug
$625.00

file-alt Citations

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