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GALNT11 (NM_022087) Human Untagged Clone

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SKU
SC112822
GALNT11 (untagged)-Human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) (GALNT11)
  $567.00
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol GALNT11
Synonyms GALNAC-T11; GALNACT11
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC112822 sequence for NM_022087 edited (data generated by NextGen Sequencing)
ATGGGAAGTGTCACAGTTCGGTATTTCTGTTATGGGTGCCTTTTTACATCTGCGACCTGG
ACAGTTTTGCTTTTTGTTTATTTCAACTTCAGTGAAGTGACTCAGCCACTTAAGAATGTG
CCCGTCAAGGGGTCTGGGCCCCACGGACCATCTCCAAAAAAATTCTATCCCCGTTTCACT
CGAGGCCCAAGTCGAGTGCTCGAGCCACAGTTCAAAGCAAACAAAATTGACGATGTGATA
GACAGTCGTGTTGAAGATCCAGAAGAAGGCCACTTGAAATTCTCTTCTGAATTAGGTATG
ATTTTTAATGAACGCGATCAAGAGTTGAGAGACTTGGGCTATCAGAAACATGCTTTTAAT
ATGCTTATCAGTGACCGCTTGGGCTACCACAGAGATGTGCCAGACACAAGGAATGCAGCA
TGTAAAGAAAAGTTCTACCCACCTGACCTGCCAGCTGCTAGTGTTGTTATCTGTTTCTAT
AATGAAGCGTTTTCTGCCTTGCTTCGGACAGTGCACAGTGTCATAGACCGCACGCCAGCA
CACCTGCTTCATGAGATCATCCTTGTGGATGATGATAGTGACTTTGATGATTTGAAAGGA
GAACTAGATGAATATGTCCAAAAATACCTCCCTGGAAAAATTAAAGTCATAAGAAATACA
AAGCGTGAGGGGTTGATTCGAGGGAGAATGATTGGCGCGGCCCACGCGACAGGAGAAGTC
CTTGTGTTCCTGGACAGCCACTGTGAAGTGAATGTGATGTGGCTGCAGCCCTTGCTGGCC
GCCATCCGTGAGGACCGGCACACCGTGGTGTGCCCAGTGATTGACATCATCAGCGCCGAC
ACGCTGGCCTACAGCTCGTCCCCTGTCGTCCGCGGAGGGTTCAACTGGGGACTGCACTTC
AAATGGGATCTTGTCCCCCTTTCTGAGCTAGGACGAGCGGAGGGAGCCACTGCACCAATA
AAGTCACCAACAATGGCTGGAGGTTTGTTTGCCATGAACAGACAGTATTTCCATGAACTT
GGACAGTATGATAGTGGCATGGATATCTGGGGAGGAGAAAATTTGGAAATATCATTTCGG
ATCTGGATGTGTGGCGGTAAGCTCTTCATCATCCCTTGCTCTAGAGTAGGACACATTTTC
CGAAAAAGGCGACCATATGGATCTCCCGAAGGCCAGGACACCATGACACACAACTCTTTG
CGGCTGGCACATGTCTGGTTGGATGAATACAAGGAGCAGTATTTTTCCTTAAGACCTGAC
CTGAAGACGAAAAGCTATGGCAATATCAGTGAGCGTGTGGAACTGAGAAAGAAGTTGGGC
TGTAAATCATTTAAATGGTATTTGGATAATGTATACCCAGAGATGCAGATATCTGGGTCC
CACGCCAAACCCCAACAACCCATTTTTGTCAATAGAGGGCCAAAACGACCCAAAGTCCTT
CAACGTGGAAGGCTCTATCACCTCCAGACCAACAAATGCCTGGTGGCCCAGGGCCGCCCA
AGTCAGAAGGGAGGTCTCGTGGTGCTTAAGGCCTGTGACTACAGTGACCCAAATCAGATC
TGGATCTATAATGAAGAGCATGAATTGGTTTTAAATAGTCTCCTTTGTCTAGATATGTCA
GAGACTCGCTCATCAGACCCGCCACGGCTCATGAAATGCCACGGGTCAGGAGGATCCCAG
CAGTGGACCTTTGGGAAAAACAATCGGCTATACCAGGTGTCGGTTGGACAGTGCCTGAGA
GCAGTGGATCCCCTGGGTCAGAAGGGCTCTGTCGCCATGGCGATCTGCGATGGCTCCTCT
TCACAGCAGTGGCATTTGGAAGGTTAA

Clone variation with respect to NM_022087.2
5' Read Nucleotide Sequence
>OriGene 5' read for NM_022087 unedited
GTATACGACTCACTATAGGGCGGCCGCGATTCGGCACGAGGGTACTATCCATACATCTTC
TTGTATTTGAATATCCGTTAACTGTACGCATAGTGGTCCTACTTGGTGGTTTGGAAAACA
GTGATTCTGTATTTGGTGGATGGTTTAAAGTATACTGAAGTGTCTAACATATTTATTCTT
CTTTTTTAGGAAATTGACAATGGCCCTTCAGCTATGCTAGGTCTATAATGGGAAGTGTCA
CAGTTCGGTATTTCTGTTATGGGTGCCTTTTTACATCTGCGACCTGGACAGTTTTGCTTT
TTGTTTATTTCAACTTCAGTGAAGTGACTCAGCCACTTAAGAATGTGCCCGTCAAGGGGT
CTGGGCCCCACGGACCATCTCCAAAAAAATTCTATCCCCGTTTCACTCGAGGCCCAAGTC
GAGTGCTCGAGCCACAGTTCAAAGCAAACAAAATTGACGATGTGATAGACAGTCGTGTTG
AAGATCCAGAAGAAGGCCACTTGAAATTCTCTTCTGAATTAGGTATGATTTTTAATGAAC
GCGATCAAGAGTTGAGAGACTTGGGCTATCAGAAACATGCTTTTAATATGCTTATCAGTG
ACCGCTTGNGCTACCACAGAGATGTGCCAGACACAAGGAATGCAGCATGTAAAGAAAAGT
TCTACCCACCTGACCTGCCAGCTGCTAGNNNGTGTATCTGTTTCTATAATGAAGCGTTTT
CTGCCTTGCTTCGGACAGTGCACAGTGTCATAGACCGCACCCAGCACACCTGCTNATGAG
ATCATNCTTGGGATGATGATAGTGACTTTGATGATTGGAAAGGAGAACTAGATGATATGT
CAAAATACCTCCCTGAANAATNAAGTCATAGAAATACAAGCGTGAGGGGTTGATTCNAGG
AGATGATTGGCGCCGCCCACCAAAGGAAAATTCTGTGTCCTGNACGCCACTGGAGTGATG
GAGN
3' Read Nucleotide Sequence
>OriGene 3' read for NM_022087 unedited
GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTATCAAAGGATTCTTTA
TTATGTAGATTGTATCATAATTCATCAAAATAATTTTATAATTAACTGCCATACTGTCTT
ATAAATGATGCCTTCTGAAGTTAAACATAATATAGATTCAGTTTTTTAAAATGATCTACT
TACAACATACTAAACAAATAATAGAAGTTTTTTTTTTTTTTAAAGCACTATCTCCTATGA
AGTCTAAGAAAGGAAATCATGACAAGTTCCTGATCAGATAAAAACCACTGCATCATTAAA
GGGGATTAAAAAGAGGCATAAATAAATCTGAATAGAAATATCCATTTTCCTGGGTTTTAT
CCTTCTGTACAAGCCCAATTCTAGAGTTAAAATGATACTGTGGTTTGCCTCTATAAGCAA
GAAATTCCTTAACAGCAGCTCAAACATCACCTTAATGTCCAGGTGAAACATACTCACTTC
TTCACCCGTGGACACTCACTTCTTCACCCGTGGACACTCAAAGCTCCCGTCTCTGTCAGA
CACGTGTCACCTCTGCTAACACACCCAGGCATCTCCGGGAGGACAGGGAAACTGTCATTT
TTCTCACAAATGGTTTCTGCTCCACCCAACCCCAGCTTTCCTTAAAGCCCCAACCTCCAC
ACCGGGAGGGACCCCCTGATGAAACACCGTTCCCCGCCAAGATTTCACTTTACCTTCCCA
AGGCCACTGTTGGGAAAAGAAGCCATTTATATCGCCATGGGAACAAACCCCTCCTGCACA
CTGGAACACGGCTTTAAGCACTGTCACCGCACCTTGTTTACCATTTGTTTTCACAAAGGC
CACTGGTGGGACCCCCAGACCCTGGCTTCATTACCCCTTGCCATCTCAACC
Restriction Sites NotI-NotI |
ACCN NM_022087
Insert Size 2940 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_022087.1, NP_071370.1
RefSeq Size 2591 bp
RefSeq ORF 1827 bp
Locus ID 63917
UniProt ID Q8NCW6
Cytogenetics 7q36.1
Domains Glycos_transf_2, RICIN
Protein Families Transmembrane
Protein Pathways Metabolic pathways, O-Glycan biosynthesis
Summary Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1. O-glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2 than GALNT1. Not involved in glycosylation of erythropoietin (EPO).UniProtKB/Swiss-Prot Function
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
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Documents
Resources
"NM_022087" in other vectors (4)
SKU Description Size Price
RC222681 GALNT11 (Myc-DDK-tagged)-Human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) (GALNT11) 10 ug
$289.00 $566.00
RC222681L3 Lenti-ORF clone of GALNT11 (Myc-DDK-tagged)-Human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) (GALNT11) 10 ug
$866.00
RC222681L4 Lenti-ORF clone of GALNT11 (mGFP-tagged)-Human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) (GALNT11) 10 ug
$866.00
RG222681 GALNT11 (tGFP-tagged) - Human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) (GALNT11) 10 ug
$766.00

file-alt Citations

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