KCNC4 (NM_004978) Human Untagged Clone

SKU SC111648

KCNC4 (untagged)-Human potassium voltage-gated channel, Shaw-related subfamily, member 4 (KCNC4), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: KCNC4
• Synonyms: C1orf30; HKSHIIIC; KSHIIIC; KV3.4
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111648 sequence for NM_004978 edited (data generated by NextGen Sequencing); ATGATCAGCTCGGTGTGTGTCTCCTCCTACCGCGGGCGCAAGTCGGGGAACAAGCCTCCG; TCCAAAACATGTCTGAAGGAGGAGATGGCCAAGGGCGAGGCGTCGGAGAAGATCATCATC; AACGTGGGCGGCACGCGACATGAGACCTACCGCAGCACCCTGCGCACCCTACCGGGAACC; CGCCTCGCCTGGCTGGCCGACCCCGACGGCGGGGGCCGGCCCGAGACCGATGGCGGCGGT; GTGGGTAGCAGCGGCAGCAGCGGCGGCGGGGGCTGCGAGTTCTTCTTCGACAGGCACCCG; GGCGTCTTCGCCTACGTGCTCAACTACTACCGCACCGGCAAGCTGCACTGCCCCGCGGAC; GTGTGCGGGCCGCTCTTCGAAGAGGAGCTCACCTTCTGGGGCATCGACGAGACCGACGTG; GAACCCTGCTGCTGGATGACCTACCGGCAGCACCGCGACGCCGAGGAGGCGCTCGACATC; TTCGAGAGCCCGGACGGAGGCGGCAGCGGCGCGGGGCCCAGCGACGAGGCCGGCGACGAT; GAGCGGGAGCTGGCCCTGCAGCGACTGGGCCCCCACGAGGGAGGCGCGGGCCATGGCGCC; GGGTCTGGGGGCTGCCGCGGCTGGCAGCCCCGCATGTGGGCGCTCTTCGAGGATCCCTAC; TCCTCCCGGGCCGCTAGGGTAGTGGCCTTTGCCTCTCTCTTCTTCATCCTGGTCTCCATC; ACCACTTTCTGCCTGGAGACCCATGAGGCCTTTAATATCGACCGCAACGTGACAGAGATC; CTCCGCGTAGGGAACATCACCAGCGTGCACTTCCGGCGGGAGGTAGAGACAGAGCCCATC; CTGACCTACATCGAGGGCGTATGTGTGCTGTGGTTCACACTGGAGTTCCTGGTGCGCATC; GTGTGCTGCCCCGACACGCTGGACTTCGTCAAGAACCTGCTCAACATCATCGACTTTGTG; GCCATCCTGCCCTTCTACCTGGAGGTGGGGCTGAGCGGCCTGTCATCCAAGGCGGCCCGC; GACGTGCTGGGCTTCCTGCGCGTGGTGCGCTTCGTGCGCATCCTGCGTATCTTCAAGCTC; ACACGCCACTTCGTGGGGCTACGCGTGCTGGGCCACACCCTGAGGGCCAGCACCAATGAG; TTCCTGCTGCTTATCATCTTCCTGGCCCTGGGTGTGCTCATCTTTGCCACCATGATCTAC; TACGCTGAGCGCATTGGGGCCAGGCCCTCCGACCCTCGGGGTAATGACCACACCGACTTC; AAGAACATCCCCATTGGCTTCTGGTGGGCTGTGGTCACCATGACGACACTGGGCTACGGA; GACATGTACCCCAAGACGTGGTCAGGCATGCTGGTAGGGGCACTGTGTGCACTGGCTGGC; GTGCTCACCATCGCCATGCCGGTGCCTGTCATCGTCAACAACTTCGGCATGTACTACTCC; CTGGCCATGGCCAAGCAGAAGCTGCCCAAGAAACGGAAGAAGCACGTGCCACGGCCGGCG; CAGCTGGAGTCACCCATGTACTGCAAGTCTGAGGAGACTTCCCCCCGGGACAGCACCTGC; AGTGATACCAGCCCCCCTGCCCGGGAAGAGGGTATGATCGAGAGGAAACGGGCAGACTCT; AAGCAGAATGGCGATGCCAACGCAGTGCTGTCTGATGAGGAGGGAGCTGGCCTCACCCAA; CCCCTGGCCTCCTCCCCGACCCCCGAGGAGCGCCGGGCCCTGCGACGCTCCACCACTCGA; GACAGAAACAAGAAGGCAGCTGCCTGCTTCCTGCTCAGCACTGGGGACTATGCCTGCGCC; GATGGTAGTGTCCGGAAAGGCACATTCGTCCTCCGTGACCTTCCCCTTCAGCATTCACCT; GAGGCTGCATGCCCTCCAACTGCTGGGACTCTGTTCCTGCCACATTGA; ; Clone variation with respect to NM_004978.4;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004978 unedited; AATCTTCACCCGCCCGTTGNCTCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATA; AGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCC; GCGAATCGGCACGAGGAGCGTTTGTGTGTCCCGTCGTAGCGGGGGACCGCGTGTGTGCTT; GCTTCTACTTCCCCGGGTCCTCCCTCTCTGCGCCTCCCTCTCTCCGGAGCTTCCTGCCCT; AACCCCAACCACCTGTGTACCGGAGAAATCCAACTCCTCCCGCTCCGCGTCCTAGGGGGA; TAGGCAGGGGCAAGCCCAAGCCGCAGAGGGGGCCGCCACCGCCTCCTGCCTCCTCTTCGT; CTCCTCCCCCTCCCCCGTCTGACGCTGCCTCCTCGGGAAGGGTGTTTGGAGGGCAGCGGC; CGCCCCAAGCCGGAGCCCCGCAGCGCTTCTTATGATCAGCTCGGTGTGTGTCTCCTCCTA; CCGCGGGCGCAAGTCGGGGAACAAGCCTCCGTCCAAAACATGTCTGAAGGAGGAGATGGC; CAAGGGCGAGGCGTCGGAGAAGATCATCATCAACGTGGGCGGCACGCGACATGAGACCTA; CCGCAGCACCCTGCGCACCCTACCGGGAACCCGCCTCGCCTGGCTGGCCGACCCCGACGG; CGGNGGCCGGCCCGAGACCGATGGCGGCGGTGTGGGTAGCAGCGGCAGCAGCGGCGGCGN; GGGCTGCGAGTTCTTCTTCGACAGGCACCCGGGCGTCTTCGCCTACGTGCTCAACTACTA; CCGCACCGGCAAGCTGCACTGCCCCGCGGACGTGTGCGGGCCGCTCTTCGAAGAGAGCTC; ACCTTCTGGGGCATCGACGAGACCGACGTGGAACCCTGCTGCTGGATGACCCTACGGCAG; CACCGC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004978 unedited; GAACTCTATGTACGTGGCCGCCTTTANGATCGGTTTTTTTTTTTTTTTTTTTCAACAGCA; GGATCAGCAGGATGCTCCAGATGTCTTTATTGGGGCTCGAGCACAGCATGACAGTTGGAG; GCATGCAGACAGGGCACAGGGCCCAGCCTGGGCATGCCCCAGACACACACGAGGGGACAG; CTTTAGAAAAGGACTGACCAACACCAGGGAGGAGCAGGGAGGGAGGGCCAAGGGAGGGGC; AGAGGCCAAGGCTGAAGGGGTCACCTGGCCTCTGCTATTGCACGCATCCTCTGGCCACTG; ACCAGGAAGTACAGTATTGCAACTGGTCTCCTCTTGCCCAAGGCTTCCCTTCTCGGACCC; CCTGGGCCAGATGGGCAGACAGATCCTTTCCCTGCCTGTCTGCCCAGCAGCATCTTTGAC; AACAAACAGACAAAGGAGAGAGAACAAAATCAAATCTAAAAAAGACAAAATGCCCCCCTA; AGTCAAGGACATAGATGGGGTGGAGGAAGTATTGGAGGAGGCTGCAGAGGAGCCCCTGGA; AGTCCCCCCACAACGAGGATGTGGGGTGGGAGGTAAAACCCCAATCTGGGGTGGGGTGCG; GCTAGTGAAGCAGTGACCCTAGGGGGCAGTCTGGCCTTCAATAGACTTCACCAGGTTACT; TGCTGACAGGGGAAACATCCCCAAGAAGGAGCCTGGGACTACCCAGCTGGACTGGCAATT; CCAGATGCACTTTTCTGGGGACATTNCACCCCACGGTCGGCGGAAACAACCGAAATCGTG; GAAGGGGACGGGNAACTCTGGGTGGGGCAAGGGCCTATGGAAACCAGCCTAACAAGAAGA; CAAACCCCCATGGCCGGTGCCCTCCCACAAGATTTAATTTGGGTGAATC;
• Restriction Sites: NotI-NotI
• ACCN: NM_004978
• Insert Size: 4000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004978.2, NP_004969.2
• RefSeq Size: 2879 bp
• RefSeq ORF: 1908 bp
• Locus ID: 3749
• UniProt ID: Q03721
• Cytogenetics: 1p13.3
• Domains: BTB, ion_trans, K_tetra
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• Summary: The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]; Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a).