DOK5 (NM_018431) Human Untagged Clone
$300.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | DOK5 |
| Synonyms | C20orf180; IRS-6; IRS6 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_018431 |
| Insert Size | 1830 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_018431.3, NP_060901.2 |
| RefSeq Size | 1833 bp |
| RefSeq ORF | 921 bp |
| Locus ID | 55816 |
| UniProt ID | Q9P104 |
| Cytogenetics | 20q13.2 |
| Domains | IRS, PH |
| Protein Families | Druggable Genome |
| Summary | The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants. provided by RefSeq, Jun 2014 Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). |
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Documents
| Product Manuals |
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Resources
"NM_018431" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC211718 | DOK5 (Myc-DDK-tagged)-Human docking protein 5 (DOK5) | 10 ug |
$300.00
|
|
| RC211718L3 | Lenti ORF clone of Human docking protein 5 (DOK5), Myc-DDK-tagged | 10 ug |
$600.00
|
|
| RC211718L4 | Lenti ORF clone of Human docking protein 5 (DOK5), mGFP tagged | 10 ug |
$600.00
|
|
| RG211718 | DOK5 (tGFP-tagged) - Human docking protein 5 (DOK5) | 10 ug |
$489.00
$500.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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