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GH2 (NM_022557) Human Untagged Clone

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SKU
SC109273
GH2 (untagged)-Human growth hormone 2 (GH2), transcript variant 2
  $300.00
4 Weeks*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol GH2
Synonyms GH-V; GHB2; GHL; GHV; hGH-V
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>NCBI ORF sequence for NM_022557, the custom clone sequence may differ by one or more nucleotides


ATGGCTGCAGGCTCCCGGACGTCCCTGCTCCTGGCTTTTGGCCTGCTCTGCCTGTCCTGGCTTCAAGAGG
GCAGTGCCTTCCCAACCATTCCCTTATCCAGGCTTTTTGACAACGCTATGCTCCGCGCCCGTCGCCTGTA
CCAGCTGGCATATGACACCTATCAGGAGTTTGAAGAAGCCTATATCCTGAAGGAGCAGAAGTATTCATTC
CTGCAGAACCCCCAGACCTCCCTCTGCTTCTCAGAGTCTATTCCAACACCTTCCAACAGGGTGAAAACGC
AGCAGAAATCTAACCTAGAGCTGCTCCGCATCTCCCTGCTGCTCATCCAGTCATGGCTGGAGCCCGTGCA
GCTCCTCAGGAGCGTCTTCGCCAACAGCCTGGTGTATGGCGCCTCGGACAGCAACGTCTATCGCCACCTG
AAGGACCTAGAGGAAGGCATCCAAACGCTGATGTGGGTGAGGGTGGCACCAGGGATCCCCAATCCTGGGG
CCCCACTGGCTTCCAGGGACTGGGGAGAGAAACACTGCTGCCCTCTTTTTAGCAGTCAGGCGCTGACCCA
AGAGAACTCACCGTATTCTTCATTTCCCCTCGTGAATCCTCCAGGCCTTTCTCTACAACCTGGAGGGGAG
GGAGGAAAATGGATGAATGAGAGAGGGAGGGAACAGTGCCCAAGCGCTTGGCCTCTCCTTCTCTTCCTTC
ACTTTGCAGAGGCTGGAAGATGGCAGCCCCCGGACTGGGCAGATCTTCAATCAGTCCTACAGCAAGTTTG
A
Restriction Sites Please inquire |
ACCN NM_022557
Insert Size 860 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_022557.2, NP_072051.1
RefSeq Size 1078 bp
RefSeq ORF 771 bp
Locus ID 2689
UniProt ID P01242
Cytogenetics 17q23.3
Domains hormone
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction
Summary The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. provided by RefSeq, Jul 2008
Transcript Variant: This variant (2) utilizes intron D to generate the longest isoform (2), which diverges from all other GH isoforms in the carboxy terminus.
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"NM_022557" in other vectors (4)
SKU Description Size Price
RC218142 GH2 (Myc-DDK-tagged)-Human growth hormone 2 (GH2), transcript variant 2 10 ug
$300.00
RC218142L3 Lenti ORF clone of Human growth hormone 2 (GH2), transcript variant 2, Myc-DDK-tagged 10 ug
$600.00
RC218142L4 Lenti ORF clone of Human growth hormone 2 (GH2), transcript variant 2, mGFP tagged 10 ug
$600.00
RG218142 GH2 (tGFP-tagged) - Human growth hormone 2 (GH2), transcript variant 2 10 ug
$500.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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