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CAMK2B (NM_172081) Human Untagged Clone

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SKU
SC109006
CAMK2B (untagged)-Human calcium/calmodulin-dependent protein kinase II beta (CAMK2B), transcript variant 5
  $469.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol CAMK2B
Synonyms CAM2; CAMK2; CAMKB; CaMKIIbeta; MRD54
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC109006 sequence for NM_172081 edited (data generated by NextGen Sequencing)
ATGGCCACCACGGTGACCTGCACCCGCTTCACCGACGAGTACCAGCTCTACGAGGATATT
GGCAAGGGGGCTTTCTCTGTGGTCCGACGCTGTGTCAAGCTCTGCACCGGCCATGAGTAT
GCAGCCAAGATCATCAACACCAAGAAGCTGTCAGCCAGAGATCACCAGAAGCTGGAGAGA
GAGGCTCGGATCTGCCGCCTTCTGAAGCATTCCAACATCGTGCGTCTCCACGACAGCATC
TCCGAGGAGGGCTTCCACTACCTGGTCTTCGATCTGGTCACTGGTGGGGAGCTCTTTGAA
GACATTGTGGCGAGAGAGTACTACAGCGAGGCTGATGCCAGTCACTGTATCCAGCAGATC
CTGGAGGCCGTTCTCCATTGTCACCAAATGGGGGTCGTCCACAGAGACCTCAAGCCGGAG
AACCTGCTTCTGGCCAGCAAGTGCAAAGGGGCTGCAGTGAAGCTGGCAGACTTCGGCCTA
GCTATCGAGGTGCAGGGGGACCAGCAGGCATGGTTTGGTTTCGCTGGCACACCAGGCTAC
CTGTCCCCTGAGGTCCTTCGCAAAGAGGCGTATGGCAAGCCCGTGGACATCTGGGCATGT
GGGGTGATCCTGTACATCCTGCTCGTGGGCTACCCACCCTTCTGGGACGAGGACCAGCAC
AAGCTGTACCAGCAGATCAAGGCTGGTGCCTATGACTTCCCGTCCCCTGAGTGGGACACC
GTCACTCCTGAAGCCAAAAACCTCATCAACCAGATGCTGACCATCAACCCTGCCAAGCGC
ATCACAGCCCATGAGGCCCTGAAGCACCCGTGGGTCTGCCAACGCTCCACGGTAGCATCC
ATGATGCACAGACAGGAGACTGTGGAGTGTCTGAAAAAGTTCAATGCCAGGAGAAAGCTC
AAGGGAGCCATCCTCACCACCATGCTGGCCACACGGAATTTCTCAGCAGCCAAGAGTTTA
CTCAACAAGAAAGCAGATGGAGTCAAGCCCCAGACGAATAGCACCAAAAACAGTGCAGCC
GCCACCAGCCCCAAAGGGACGCTTCCTCCTGCCGCCCTGGAGTCTTCTGACAGTGCCAAT
ACCACCATAGAGGATGAAGACGCTAAAGCCCGGAAGCAGGAGATCATTAAGACCACGGAG
CAGCTCATCGAGGCCGTCAACAACGGTGACTTTGAGGCCTACGCGAAAATCTGTGACCCA
GGGCTGACCTCGTTTGAGCCTGAAGCACTGGGCAACCTGGTTGAAGGGATGGACTTCCAC
AGATTCTACTTCGAGAACCTGCTGGCCAAGAACAGCAAGCCGATCCACACGACCATCCTG
AACCCACACGTGCACGTCATTGGAGAGGATGCCGCCTGCATCGCTTACATCCGGCTCACG
CAGTACATTGACGGGCAGGGCCGGCCCCGCACCAGCCAGTCTGAGGAGACCCGCGTGTGG
CACCGCCGCGACGGCAAGTGGCAGAACGTGCACTTCCACTGCTCGGGCGCGCCTGTGGCC
CCGCTGCAGTGA

Clone variation with respect to NM_172081.2
582 t=>c
5' Read Nucleotide Sequence
>OriGene 5' read for NM_172081 unedited
ATCCCGCCCGTTGCCGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGA
GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATT
CGGCACGAGGGCGGCGCGCTCCTGGCGAGGACGGAGCGAGCAGATCTCGCGTGCGCTCGC
CGCCCGGCGCAGCCCAGCCCGGCCCCCGCCTGGCGCCGCGAGCCGAGGTGTCTCCCGCGC
CCGCGCCCGTGTCGCCGCCGTGCCCGCGAGCGGGAGCCGGAGTCGCCGCCGCCCGAGCGC
AGCCGAGCGCACGCCGAGCCCGTCCGCCGCCGCCATGGCCACCACGGTGACCTGCACCCG
CTTCACCGACGAGTACCAGCTCTACGAGGATATTGGCAAGGGGGCTTTCTCTGTGGTCCG
ACGCTGTGTCAAGCTCTGCACCGGCCATGAGTATGCAGCCAAGATCATCAACACCAAGAA
GCTGTCAGCCAGAGATCACCAGAAGCTGGAGAGAGAGGCTCGGATCTGCCGCCTTCTGAA
GCATTCCAACATCGTGCGTCTCCACGACAGCATCTCCGAGGAGGGCTTCCACTACCTGGT
CTTCGATCTGGTCACTGGTGGGGAGCTCTTTGAAGACATTGTGGCGAGAGAGTACTACAG
CGAGGCTGATGCCAGTCACTGTATCCCGCAGATCCCGGAGGCCGTTCTCCATTGGCACCA
AATGGTGGTCGGCCACAGAGACCTTAAGCCGGAGAACCTGCTTCCGGCCCGCAAGTGCCA
AGGGGCTGCACTGGAGCCTGCAGACTTCGCCCTCCTATCCAGGTGCAGGGGCACCCCAGG
CATGGGTTGGTTTCCCTGGCACACCAGGTTCACTGGCCCCTGGAGTTCTTCGCAAAAAGC
CTATGGGAGACCTTGGACATCTGGCCGGTGGGGTGACCCCGCACT
Restriction Sites Please inquire |
ACCN NM_172081
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_172081.1, NP_742078.1
RefSeq Size 1949 bp
RefSeq ORF 1512 bp
Locus ID 816
UniProt ID Q13554
Cytogenetics 7p13
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Calcium signaling pathway, ErbB signaling pathway, Glioma, GnRH signaling pathway, Long-term potentiation, Melanogenesis, Neurotrophin signaling pathway, Olfactory transduction, Oocyte meiosis, Wnt signaling pathway
Summary The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. provided by RefSeq, May 2014
Transcript Variant: This variant (5), also known as beta e', lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (5), also known as beta e' subunit, that is missing an internal segment compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.
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Documents
Resources
"NM_172081" in other vectors (6)
SKU Description Size Price
RC205669 CAMK2B (Myc-DDK-tagged)-Human calcium/calmodulin-dependent protein kinase II beta (CAMK2B), transcript variant 5 10 ug
$468.00
RC205669L1 Lenti ORF clone of Human calcium/calmodulin-dependent protein kinase II beta (CAMK2B), transcript variant 5, Myc-DDK-tagged 10 ug
$768.00
RC205669L2 Lenti ORF clone of Human calcium/calmodulin-dependent protein kinase II beta (CAMK2B), transcript variant 5, mGFP tagged 10 ug
$768.00
RC205669L3 Lenti ORF clone of Human calcium/calmodulin-dependent protein kinase II beta (CAMK2B), transcript variant 5, Myc-DDK-tagged 10 ug
$768.00
RC205669L4 Lenti ORF clone of Human calcium/calmodulin-dependent protein kinase II beta (CAMK2B), transcript variant 5, mGFP tagged 10 ug
$768.00
RG205669 CAMK2B (tGFP-tagged) - Human calcium/calmodulin-dependent protein kinase II beta (CAMK2B), transcript variant 5 10 ug
$668.00

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