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COPS8 (NM_006710) Human Untagged Clone

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SKU
SC108821
COPS8 (untagged)-Human COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) (COPS8), transcript variant 1
  $300.00
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol COPS8
Synonyms COP9; CSN8; SGN8
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC108821 sequence for NM_006710 edited (data generated by NextGen Sequencing)
ATGCCAGTGGCGGTGATGGCGGAAAGCGCCTTTAGTTTCAAAAAGTTGCTGGATCAGTGC
GAGAACCAGGAGCTCGAGGCCCCTGGAGGAATTGCTACACCCCCAGTGTATGGTCAGCTT
CTAGCTTTATATTTGCTCCATAATGACATGAATAATGCAAGATATCTTTGGAAAAGAATA
CCACCTGCTATAAAATCTGCAAATTCTGAACTTGGGGGAATTTGGTCAGTAGGACAAAGA
ATCTGGCAGAGAGATTTCCCTGGGATCTATACAACCATCAACGCTCACCAGTGGTCTGAG
ACGGTCCAGCCAATTATGGAAGCACTTAGAGATGCAACAAGGAGACGCGCCTTTGCCCTG
GTCTCTCAAGCGTATACTTCAATCATCGCCGATGATTTTGCAGCCTTTGTTGGACTTCCT
GTAGAAGAGGCTGTGAAAGGCATATTAGAACAAGGATGGCAAGCTGATTCCACCACAAGA
ATGGTTCTGCCCAGAAAGCCAGTTGCAGGGGCCCTGGATGTTTCCTTTAACAAGTTTATT
CCCTTATCAGAGCCTGCTCCAGTTCCCCCAATACCCAATGAACAGCAGTTAGCCAGACTG
ACGGATTATGTGGCTTTCCTTGAAAACTGA

Clone variation with respect to NM_006710.4
5' Read Nucleotide Sequence
>OriGene 5' read for NM_006710 unedited
GTATACGACTCACTATAGGGCGGCCGCGATTCGGCACGAGGCGACGCCTGAGGGACAGTC
TGGGGTTTGGCTGTCCGGACGGTGCAGCGGCGAGGCCGGCCGCGAAGATGCCAGTGGCGG
TGATGGCGGAAAGCGCCTTTAGTTTCAAAAAGTTGCTGGATCAGTGCGAGAACCAGGAGC
TCGAGGCCCCTGGAGGAATTGCTACACCCCCAGTGTATGGTCAGCTTCTAGCTTTATATT
TGCTCCATAATGACATGAATAATGCAAGATATCTTTGGAAAAGAATACCACCTGCTATAA
AATCTGCAAATTCTGAACTTGGGGGAATTTGGTCAGTAGGACAAAGAATCTGGCAGAGAG
ATTTCCCTGGGATCTATACAACCATCAACGCTCACCAGTGGTCTGAGACGGTCCAGCCAA
TTATGGAAGCACTTAGAGATGCAACAAGGAGACGCGCCTTTGCCCTGGTCTCTCAAGCGT
ATACTTCAATCATCGCCGATGATTTTGCAGCCTTTGTTGGACTTCCTGTAGAAGAGGCTG
TGAAAGGCATATTAGAACAAGGATGGCAAGCTGATTCCACCACAAGAATGGTTCTGCCCA
GAAAGCCAGTTGCAGGGGCCCTGGATGTTTCCTTTAACAAGTTTATTCCCTTATCAGAGC
CTGCTCCCAGTTCCCCCAATACCCAATGAACAGCAGTTACCCAGACTGACGGATTATGTG
GCTTTCCTTGAAAACTGATTTATCACTCTGAGTCCAGAATTCTCTTTAGAATCCTGTATA
CTGACCAACGTAAAAAATGTAAAGTTTGTATTTTCAATTATTGAATGGCTTAGCACCTCA
CATTCTTTCTTTGGGTAAAATCCTTTTGAATTTAGATTTCTTTTTCCTTTTGCCTTACCG
TTTT
3' Read Nucleotide Sequence
>OriGene 3' read for NM_006710 unedited
TGTCTCCTGCTTCTTCGCTTCTCTCCCTCCCTTCCTTCTCCCCCCCCCCCACAACTTTAT
CTCTAGANCNCGNCGGCCCCGTCTATTCTCANCGATNCGNGNTCTCTTTTCTTCTTTTCT
TCTTTTACAGTCTAAATATTACTATTGAACAAATGCAGAGTAAATGAACTAAGGGCTGTT
ATAACCTTAAGTTACAACAAACAACTTCAAATATTCACAGGGCTGTCACACAGAGAATGA
AAGACTTGCTCAGTATTTCTCCAAAGGGCAGAACTTGAGCCAAGCGATAAATATAACCAA
CCAATGGGCTGCAGGATACTTGTACAAAGCGTATCATGTATCTTCATAGCTTCTTTGCCC
ATATAATGCATTCCACACTTAAGTTTCTCCTTCTAAAAGGCGACAGCACAAGTTAATATG
TCTCATAAATGTCTTAAATAAGCCGCATTTTTCATGGCAAGCCCTCCACTGCCAGCAATG
GATATACTCACACTATTGGAAAAAATCTACAAGTTAACAAACTGGTTTAGTATGGAAATG
GTCTATTTGTTCCCTCCACCTATGTCCCCTGTATCTTACATTAGTGGCCTCCAGGAGGTG
GGGGGTGAAAAAGAGACCATGCCCTCCCAACCAGGCGAATCATAACCTCCCCCGTGATTC
AAATACTGGGCCTCGGGGACCATCTTTTTCTCCGGCCCACTCGACCCTTCTCTTCCTAAC
CACAGCACATCATCAAATACCGCTTGCCCTGGGACAAAGAAAAGACCCCCGCCACACACT
ATTCTACCTGAAAAAGGAAAATTTTATTTTATACCCCACTAAAAAACCCAACTGCCCACT
GCCGCGCTCCCTCCACATTTTTAACCCCCCAAAACGCGACCTGTTTTAACCCCCCCCCCC
AACCTGTTTCCGACCAAAGGAACACAATATACCCCTAAATTCTATAGTTATCCTACCCCA
CTCCACGGAACCTTGGGCGCTCCAACATCTCCAATG
Restriction Sites NotI-NotI |
ACCN NM_006710
Insert Size 1710 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_006710.4, NP_006701.1
RefSeq Size 2274 bp
RefSeq ORF 630 bp
Locus ID 10920
UniProt ID Q99627
Cytogenetics 2q37.3
Summary The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. provided by RefSeq, Jul 2008
Transcript Variant: This variant (1) encodes the longer isoform (1).
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Documents
Resources
"NM_006710" in other vectors (7)
SKU Description Size Price
RC207324 COPS8 (Myc-DDK-tagged)-Human COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) (COPS8), transcript variant 1 10 ug
$300.00
RC207324L1 Lenti ORF clone of Human COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) (COPS8), transcript variant 1, Myc-DDK-tagged 10 ug
$600.00
RC207324L2 Lenti ORF clone of Human COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) (COPS8), transcript variant 1, mGFP tagged 10 ug
$600.00
RC207324L3 Lenti ORF clone of Human COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) (COPS8), transcript variant 1, Myc-DDK-tagged 10 ug
$600.00
RC207324L4 Lenti ORF clone of Human COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) (COPS8), transcript variant 1, mGFP tagged 10 ug
$600.00
RG207324 COPS8 (tGFP-tagged) - Human COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) (COPS8), transcript variant 1 10 ug
$489.00 $500.00
SC322137 COPS8 (untagged)-Human COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) (COPS8), transcript variant 1 10 ug
$300.00

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