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LILRB3 (NM_006864) Human Untagged Clone

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SKU
SC108531
LILRB3 (untagged)-Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 (LILRB3), transcript variant 2
  $588.00
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol LILRB3
Synonyms CD85A; HL9; ILT-5; ILT5; LILRA6; LIR-3; LIR3; PIR-B; PIRB
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_006864 edited
GAATTCGGCACGAGGCTGGGGCCCCTGGGAGGAGACGCCATGATCCCCACCTTCACGGCT
CTGCTCTGCCTCGGGCTGAGTCTGGGCCCCAGGACCCACATGCAGGCAGGGCCCCTCCCC
AAACCCACCCTCTGGGCTGAGCCAGGCTCTGTGATCAGCTGGGGGAACTCTGTGACCATC
TGGTGTCAGGGGACCCTGGAGGCTCGGGAGTACCGTCTGGATAAAGAGGAAAGCCCAGCA
CCCTGGGACAGACAGAACCCACTGGAGCCCAAGAACAAGGCCAGATTCTCCATCCCATCC
ATGACAGAGGACTATGCAGGGAGATACCGCTGTTACTATCGCAGCCCTGTAGGCTGGTCA
CAGCCCAGTGACCCCCTGGAGCTGGTGATGACAGGAGCCTACAGTAAACCCACCCTTTCA
GCCCTGCCGAGTCCTCTTGTGACCTCAGGAAAGAGCGTGACCCTGCTGTGTCAGTCACGG
AGCCCAATGGACACTTTCCTTCTGATCAAGGAGCGGGCAGCCCATCCCCTACTGCATCTG
AGATCAGAGCACGGAGCTCAGCAGCACCAGGCTGAATTCCCCATGAGTCCTGTGACCTCA
GTGCACGGGGGGACCTACAGGTGCTTCAGCTCACACGGCTTCTCCCACTACCTGCTGTCA
CACCCCAGTGACCCCCTGGAGCTCATAGTCTCAGGATCCTTGGAGGGTCCCAGGCCCTCA
CCCACAAGGTCCGTCTCAACAGCTGCAGGCCCTGAGGACCAGCCCCTCATGCCTACAGGG
TCAGTCCCCCACAGTGGTCTGAGAAGGCACTGGGAGGTACTGATCGGGGTCTTGGTGGTC
TCCATCCTGCTTCTCTCCCTCCTCCTCTTCCTCCTCCTCCAACACTGGCGTCAGGGAAAA
CACAGGACATTGGCCCAGAGACAGGCTGATTTCCAACGTCCTCCAGGGGCTGCCGAGCCA
GAGCCCAAGGACGGGGGCCTACAGAGGAGGTCCAGCCCAGCTGCTGACGTCCAGGGAGAA
AACTTCTGTGCTGCCGTGAAGAACACACAGCCTGAGGACGGGGTGGAAATGGACACTCGG
AGCCCACACGATGAAGACCCCCAGGCAGTGACGTATGCCAAGGTGAAACACTCCAGACCT
AGGAGAGAAATGGCCTCTCCTCCCTCCCCACTGTCTGGGGAATTCCTGGACACAAAGGAC
AGACAGGCAGAAGAGGACAGACAGATGGACACTGAGGCTGCTGCATCTGAAGCCCCCCAG
GATGTGACCTACGCCCGGCTGCACAGCTTTACCCTCAGACAGAAGGCAACTGAGCCTCCT
CCATCCCAGGAAGGGGCCTCTCCAGCTGAGCCCAGTGTCTATGCCACTCTGGCCATCCAC
TAATCCAGGGGGGACCCAGACCCCACAAGCCATGGAGACTCAGGACCCCAGAAGGCATGG
AAGCTGCCTCCAGTAGACATCACTGAACCCCAGCCAGCCCAGACCCCTGACACAGACCAC
TAGAAGATTCCGGGAACGTTGGGAGTCACCTGATTCTGCAAAGATAAATAATATCCCTGC
ATTATCAAAATAAAGTAGCAGACCTCTCAAAAAAAAAAAAAAAAAACTCGAC
3' Read Nucleotide Sequence
>OriGene 3' read for NM_006864 unedited
ACCGCGGCCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTGAGAGGTCTGCTACTT
TATTTTGATAATGCAGGGATATTATTTATCTTTGCAGAATCAGGTGACTCCCAACGTTCC
CGGAATCTTCTAGTGGTCTGTGTCAGGGGTCTGGGCTGGCTGGGGTTCAGTGATGTCTAC
TGGAGGCAGCTTCCATGCCTTCTGGGGTCCTGAGTCTCCATGGCTTGTGGGGTCTGGGTC
CCCCCTGGATTAGTGGATGGCCAGAGTGGCATAGACACTGGGCTCAGCTGGAGAGGCCCC
TTCCTGGGATGGAGGAGGCTCAGTTGCCTTCTGTCTGAGGGTAAAGCTGTGCAGCCGGGC
GTAGGTCACATCCTGGGGGGCTTCAGATGCAGCAGCCTCAGTGTCCATCTGTCTGTCCTC
TTCTGCCTGTCTGTCCTTTGTGTCCAGGAATTCCCCAGACAGTGGGGAGGGAGGAGAGGC
CATTTCTCTCCTAGGTCTGGAGTGTTTCACCTTGGCATACGTCACTGCCTGNGGGTCTTC
ATCGTGTGGGCTCCGAGTGTCCATTTCCACCCCGTCCTCAGGCTGTGTGTTCTTCACGGC
AGCACAGAAGTTTTCTCCCTGGACGTCAGCAGCTGGGCTGGACCTCCTCTGTAGGCCCCC
GTCCTTGGGCTCTGGGCTCGCAGCCCCTGGNAGACGTTGGAATTCAGCCTGTCTCTGGGC
CAATGTCCTGTGTTTTCCCTGACGCCAGNTGTGGANGAGGGAGAATAGNNAGANNGGANA
NAANCCCGATGGGGCACCCCCAAGACCCCGATCAGTACCTTCCAGTGCCTTCTAGGACAC
TGTTGTGGGACTGACCCTTGTAGCATGAGGGGGTTGGCCCTCACGGCCTCCCCCTGTTGA
AACGGACCTCTGGGTTGAGGCCCGCCACCCTCTCAGGACTCTGGATATTAGCCCCACGGG
TCCCCCGGGTGGTCTCCTCTACCCCCCACACCCTTCCCACATCTCCGCTCTCCCCTCCCC
TTGGCACACAT
Restriction Sites NotI-NotI |
ACCN NM_006864
Insert Size 1610 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_006864.1, NP_006855.1
RefSeq Size 2170 bp
RefSeq ORF 1896 bp
Locus ID 11025
Cytogenetics 19q13.42
Domains ig, IG, IGc2
Protein Families Druggable Genome, Transmembrane
Protein Pathways B cell receptor signaling pathway
Summary This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform 2) is 1 aa shorter than isoform 1.
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Documents
Resources
"NM_006864" in other vectors (6)
SKU Description Size Price
RC211228 LILRB3 (Myc-DDK-tagged)-Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 (LILRB3), transcript variant 2 10 ug
$587.00
RC211228L1 Lenti ORF clone of Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 (LILRB3), transcript variant 2, Myc-DDK-tagged 10 ug
$887.00
RC211228L2 Lenti ORF clone of Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 (LILRB3), transcript variant 2, mGFP tagged 10 ug
$887.00
RC211228L3 Lenti ORF clone of Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 (LILRB3), transcript variant 2, Myc-DDK-tagged 10 ug
$887.00
RC211228L4 Lenti ORF clone of Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 (LILRB3), transcript variant 2, mGFP tagged 10 ug
$887.00
RG211228 LILRB3 (tGFP-tagged) - Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 (LILRB3), transcript variant 2 10 ug
$787.00

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