Rabbit BDNF ELISA KIT (1 x 96 wells)

SKU
EA102787
Sandwich High Sensitivity ELISA kit for Quantitative Detection of rabbit BDNF. 96wells/kit, with removable strips.
  $625.00
3 Weeks*
Specifications
Specifications
Product Data
Species Rabbit
Format 8x12 divisible strips
Assay Type Sandwich ELISA kit of Quantitative Detection for Rabbit BDNF
Assay Length 3.5 hours incubations; 1 hour washing and analyzing samples
Signal Colorimetric
Curve Range 31.2pg/ml-2000pg/ml
Specificity This kit is used for quantitative detection of Rabbit BDNF
Sensitivity <15pg/ml
Reactivity Rabbit
Cross Reactivity There is no detectable cross-reactivity with other relevant proteins.
Components
  • Description|Quantity
  • Pre-coated 96-well strip microplate|1
  • Standard|2 vials
  • Biotinylated antibody (100x)|100ul
  • Avidin-Biotin-Peroxidase Complex (100x)|100ul
  • Sample Diluent|30ml
  • Antibody Diluent|12ml
  • Avidin-Biotin-Peroxidase Diluent|12ml
  • Color Developing Reagent (TMB)|10ml
  • Stop Solution|10ml
  • Wash Buffer (25x)|20ml
  • Adhesive plate sealers|4
Background Brain-derived neurotrophic factor(BDNF) is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. It is a secreted protein with the molecular weight of 27.8kDa, consisting of 247 amino acids. It is known to promote neuronal survival and differentiation. BDNF shares substantial amino acid sequence identity with nerve growth factor(NGF). BDNF and neurotrophin-3(NT-3) are two recently cloned neurotrophic factors that are homologous to NGF. mRNA products of the BDNF and NT-3 genes are detected in the adult rabbit brain, suggesting that these proteins are involved in the maintenance of the adult nervous system. BDNF and other neurotrophins are critically involved in long-term potentiation(LTP). BDNF-mediated LTP is induced postsynaptically. BDNF has trophic effects on serotonergic(5-HT) neurons in the central nervous system. BDNF has an essential maintenance function in the regulation of anxiety-related behavior and in food intake through central mediators in both the basal and fasted state. It plays a role in treating breathing disorders such as respiratory insufficiency after spinal injury. The mature form of BDNF is identical in all mammals examined, and the gene encoding rabbit BDNF to chromosome 11, band p13.
Gene Symbol BDNF
Locus ID 100356949
Shipping Blue Ice
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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