Mouse Cfh ELISA KIT (1 x 96 wells)
Specifications
| Product Data | |
| Species | Mouse |
|---|---|
| Format | 8x12 divisible strips |
| Assay Type | Sandwich ELISA kit of Quantitative Detection for mouse CFH |
| Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
| Signal | Colorimetric |
| Curve Range | 0.78ng/ml-50ng/ml |
| Specificity | This kit is used for quantitative detection of mouse CFH |
| Sensitivity | <20pg/ml |
| Reactivity | Mouse |
| Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Components |
|
| Background | Complement factor H (CFH), originally known as beta-1H globulin, is a serum glycoprotein that regulates the function of the alternativecomplement pathway in fluid phase and on cellular surfaces. It binds to C3b, accelerates the decay of the alternative pathway convertase C3bBb, and also acts as a cofactor for complement factor I, another C3b inhibitor. The CFH gene is located on chromosome 1q32-q32.1 within a cluster of genes encoding the regulatory complement components of the activation of C3 (RCA for 'regulators of complement activation'). This gene cluster includes decay-accelerating factor (DAF), C4-binding protein (C4BPA and C4BPB), and the factor H-related genes CFHR1, CFHR2, CFHR3, CFHR4, and CFHR5, among others. The gene family has arisen by multiple duplication events. |
| Gene Symbol | Cfh |
| Locus ID | 12628 |
| Shipping | Blue Ice |
Reviews
Documents
| Datasheet | |
| SDS | |
Citations
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