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Human TNFRSF14/HVEM ELISA Kit

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SKU
EA100726
Human TNFRSF14/HVEM ELISA Kit
  $755.00
3 Weeks*
Specifications
Specifications
Product Data
Species Human
Assay Type Sandwich ELISA kit of Quantitative Detection for Human TNFRSF14/HVEM
Assay Length 3.5 hours incubations; 1 hour washing and analyzing samples
Signal Colorimetric
Curve Range 15.6pg/ml-1000pg/ml
Sample Type Cell culture supernates, serum and plasma(heparin, EDTA).
Sample Volume 100 ul
Specificity This kit is used for quantitative detection of human TNFRSF14
Sensitivity <1pg/ml
Reactivity Human
Cross Reactivity There is no detectable cross-reactivity with other relevant proteins.
Interference No significant interference observed with available related molecules.
Components
  • 96-well plate precoated with anti- human TNFRSF14 antibody 1
  • Lyophilized recombinant human TNFRSF14 standard 10ng/tubex2
  • Biotinylated anti- human TNFRSF14 antibody 130ul(dilution 1:100)
  • Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100)
  • Sample diluent buffer 30 ml
  • Antibody diluent buffer 12ml
  • ABC diluent buffer 12ml
  • TMB color developing agent 10ml
  • TMB stop solution 10ml
Background Tumor necrosis factor receptor superfamily member 14(TNFRSF14), also known as HVEM, is a protein that in humans is encoded by the TNFRSF14 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily. It is mapped to 1p36.32. HVEM plays an important role in HSV pathogenesis because it enhanced the entry of several wildtype HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T cells. HVEM and BTLA which are form a bidirectional signaling pathway can regulate cell survival and inhibitory responses between interacting cells. HVEM as an important orchestrator of mucosal immunity integrates signals from innate lymphocytes to induce optimal epithelial Stat3 activation, which indicated that targeting HVEM with agonists could improve host defense.
Gene Symbol TNFRSF14
Locus ID 8764
Shipping Blue Ice
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Documents
Resources

file-alt Citations

Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells
Boice, Salloum, Mourcin et al
Cell (2016) 167 (2), 405-418.e13 DOI: 10.1016/j.cell.2016.08.032
AI Summary: OriGene’s Human HVEM ELISA Kit (Cat # EA100726) was used to confirm HVEM protein secretion in cell culture supernatants, supporting the study’s investigation of HVEM restoration in lymphoma models.
Snippet: Human HVEM Elisa Kit, Origene, Cat # EA100726 HVEM secretion was confirmed by ELISA assay of cell culture supernatant using the Origene Human HVEM ELISA kit
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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