alpha smooth muscle Actin (ACTA2) Mouse Monoclonal Antibody [Clone ID: UMAB237]

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SKU
UM800129CF
Carrier-free (BSA/glycerol-free) ACTA2 (smooth muscle actin alpha, SMA) mouse monoclonal antibody,clone UMAB237
  $680.00
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Specifications
Specifications
Product Data
Clone Name UMAB237
Application IHC
Recommended Dilution IHC 1:3200
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Synthetic peptide corresponding to the N terminal of human alpha smooth muscle actin conjugated to KLH.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 41.8 kDa
Gene Name actin alpha 2, smooth muscle
Database Link
Synonyms AAT6; ACTSA; MYMY5
Reference Data
Protein Categories Cardiovascular diseases, Growth Factors, Intracellular Proteins
Protein Pathways Vascular smooth muscle contraction
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Other "UMAB237" antibodies (2)
SKU Description Size Price
UM800129 ACTA2 (smooth muscle actin alpha, SMA) mouse monoclonal antibody,clone UMAB237 100 ul
$610.00
UM870129 ACTA2 (smooth muscle actin alpha, SMA) mouse monoclonal antibody,clone UMAB237 30 ul
$224.00

file-alt Citations

SRC and TKS5 mediated podosome formation in fibroblasts promotes extracellular matrix invasion and pulmonary fibrosis
Barbayianni, Kanellopoulou, Fanidis et al
Nat Commun (2023) 14 (1), 5882 DOI: 10.1038/s41467-023-41614-x
Cited by 27
AI Summary: OriGene products contributed anti-SH3PXD2A (clone OTI1F5-TA811757S) and anti-α-actin (sma, clone UM87012) mouse monoclonal antibodies, which were used to detect specific proteins involved in podosome formation and fibroblast activity in this study on pulmonary fibrosis.
Snippet: … Antibodies- reagents Antibodies used in this study included anti-Tks5 (SH3 domain) rabbit monoclonal antibody (Merck, 3174822, 1:100), anti-SH3PXD2A mouse monoclonal antibody (Origene, clone OTI1F5-TA811757S, LOT F001, 1:250), col1a1 rabbit polyclonal antibody (Invitrogen, PA5-29569, LOT XK3738717 1:100), anti-A-actin (sma) mouse monoclonal antibody, (Origene, clone UM870129
FigureFigureFigure
Soluble Fraction from Lysate of a High Concentration Multi-Strain Probiotic Formulation Inhibits TGF-β1-Induced Intestinal Fibrosis on CCD-18Co Cells
Lombardi, Augello, Palumbo et al
Nutrients (2021) 13 (3) DOI: 10.3390/nu13030882
Cited by 17
AI Summary: In this study, OriGene’s human colonic fibroblast cell line CCD-18Co (Cat# CRL-1459) was used as the experimental model to investigate the anti-fibrotic effects of probiotic formulations on TGF-β1-induced intestinal fibrosis.
FigureFigureFigure
Undifferentiated myxoid lipoblastoma with PLAG1 gene rearrangement in infant
Zhou, Li, Cai et al
Pathol. Res. Pract. (2019) 216 (1), 152765 DOI: 10.1016/j.prp.2019.152765
AI Summary: In this study, OriGene’s monoclonal mouse anti-human smooth muscle actin (SMA) antibody (UMAB237) was used for immunohistochemical analysis to assist in the diagnosis and characterization of undifferentiated myxoid lipoblastoma in infants.
Snippet: dilution ready to use;Fuzhou Maixin Biotech Ltd, CHN), monoclonal mouse anti-human S100 (4C4.9, dilution ready to use;Fuzhou Maixin Biotech Ltd, CHN), monoclonal mouse anti-human smooth muscle actin (SMA) (UMAB237, dilution ready to use;OriGene Technologies Inc;- dilution ready to use;OriGene
IHC FISH
Showing 1-3 of 3 papers.
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