PD-L1 (CD274) Mouse Monoclonal Antibody [Clone ID: UMAB229]
SKU
UM800121CF
Carrier-free (BSA/glycerol-free) PD-L1/CD274 mouse monoclonal antibody, clone UMAB229
$680.00
3 Days*
Specifications
| Product Data | |
| Clone Name | UMAB229 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | IHC 1:25 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 19-290 of human CD274 (NP_054862) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 33.28 kDa |
| Gene Name | CD274 molecule |
| Database Link | |
| Synonyms | B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1 |
| Reference Data | |
| Protein Categories | ADC Targets, CAR-T Targets, CD Markers, Cytokines, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs) |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Citations
KLF12 transcriptionally regulates PD-L1 expression in non-small cell lung cancer
Pan, Zhang, Wang et al
Mol Oncol (2023)
Pan, Zhang, Wang et al
Mol Oncol (2023)
Cited by 11
Impact of Chemoembolic Regimen on Immune Cell Recruitment and Immune Checkpoint Marker Expression following Transcatheter Arterial Chemoembolization in a VX2 Rabbit Liver Tumor Model
Berz, Santana, Iseke et al
J Vasc Interv Radiol (2022) 33 (7), 764-774.e4 DOI: 10.1016/j.jvir.2022.03.026
Berz, Santana, Iseke et al
J Vasc Interv Radiol (2022) 33 (7), 764-774.e4 DOI: 10.1016/j.jvir.2022.03.026
Cited by 13
AI Summary: OriGene products—specifically the CTLA-4 antibody (UM800141), PD-1 antibody (UM800089), and PD-L1 antibody (UM800121)—were used for immunohistochemical detection and quantification of immune checkpoint marker expression in tumor tissues, enabling assessment of immune response differences among TACE regimens in the study.
Expression of PD-L1 and CD4+ tumor-infiltrating lymphocytes predict survival in head and neck squamous cell carcinoma
Fu, Zhang, Guo et al
Mol Clin Oncol (2022) 16 (3), 59 DOI: 10.3892/mco.2022.2492
Fu, Zhang, Guo et al
Mol Clin Oncol (2022) 16 (3), 59 DOI: 10.3892/mco.2022.2492
Cited by 13
AI Summary: OriGene products, specifically the PD-L1 (Cat# TA802139) and CD4 (Cat# TA506821) antibodies, were used for immunohistochemical detection of PD-L1 and CD4+ tumor-infiltrating lymphocytes in head and neck squamous cell carcinoma samples, contributing to the study’s analysis of their prognostic significance.
Showing 1-3 of 3 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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