LGR5 Mouse Monoclonal Antibody [Clone ID: UMAB210]
$680.00
3 Days*
Specifications
| Product Data | |
| Clone Name | UMAB210 |
|---|---|
| Application | 10k-ChIP, FC, IF, IHC, WB |
| Recommended Dilution | WB 1:200~2000, IHC 1:100~150 (recommended antigen retrieval buffer: TEE buffer pH 9.0), IF 1:100, FLOW 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22-543 of human LGR5 (NP_003658) produced in HEK293 cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 99.8 kDa |
| Gene Name | leucine rich repeat containing G protein-coupled receptor 5 |
| Database Link | |
| Synonyms | FEX; GPR49; GPR67; GRP49; HG38 |
| Reference Data | |
| Protein Categories | GPCR, Membrane Proteins |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Citations
Lactobacillus GG regulates the Wnt/β-catenin pathway to reinforce intestinal barrier function and alleviate necrotizing enterocolitis
Li, Chen, Sun et al
Journal of Functional Foods (2022) 97, 105243 DOI: 10.1016/j.jff.2022.105243
Li, Chen, Sun et al
Journal of Functional Foods (2022) 97, 105243 DOI: 10.1016/j.jff.2022.105243
Cited by 10
Synergistic actions of FGF2 and bone marrow transplantation mitigate radiation-induced intestinal injury
Kim, Jung, Seo et al
Cell Death Dis (2018) 9 (3), 383 DOI: 10.1038/s41419-018-0421-4
Kim, Jung, Seo et al
Cell Death Dis (2018) 9 (3), 383 DOI: 10.1038/s41419-018-0421-4
AI Summary: OriGene’s LGR5 antibody (UMAB210) was used in this study to assess intestinal stem cell marker expression, contributing to the evaluation of how FGF2 and bone marrow transplantation synergistically mitigate radiation-induced intestinal injury.
Snippet: β-catenin (ab32572, Abcam, London, UK), p-ERK (Thr202/Thr204, #9101, Cell Signaling Technology, Danvers, MA, USA), cleaved Casp3 (#9664, Cell Signaling Technology, Danvers, MA, USA), LGR5 (UMAB210, Origene, Rockville, MD, USA), α-Tubulin (sc-23948, Santa Cruz Biotechnology, Santa Cruz, CA, USA), Bax (sc-20067, Santa Cruz Biotechnology, Santa Cruz, CA, USA), and LC3B (#2775, Cell Signaling Techn
Showing 1-2 of 2 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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