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CD40 Mouse Monoclonal Antibody [Clone ID: UMAB183]

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SKU
UM800075
CD40 mouse monoclonal antibody,clone UMAB183
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated
  $610.00
In Stock*
Bulk/Customize

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View other "CD40 or NM_001250" antibodies

Specifications
Specifications
Product Data
Clone Name UMAB183
Application IHC
Recommended Dilution IHC 1:200
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 21-166 of human CD40(NP_001241) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 28.4 kDa
Gene Name CD40 molecule
Database Link
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul
Synonyms Bp50; CDW40; p50; TNFRSF5
Reference Data
Protein Categories ADC Targets, CD Markers, Immune system diseases, Membrane Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Cytokine-cytokine receptor interaction, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Viral myocarditis
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Other "UMAB183" antibodies (2)
SKU Description Size Price
UM800075CF Carrier-free (BSA/glycerol-free) CD40 mouse monoclonal antibody,clone UMAB183 100 ug
$680.00
UM870075 CD40 mouse monoclonal antibody,clone UMAB183 30 ul
$224.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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