CD3E Mouse Monoclonal Antibody [Clone ID: UMAB54]
Specifications
| Product Data | |
| Clone Name | UMAB54 |
|---|---|
| Application | IF, Simple Western, WB |
| Recommended Dilution | WB 1:500, IF 1:100 ; Simple Western 1:20-1:50 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human CD3E(NP_000724) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 20.7 kDa |
| Gene Name | CD3e molecule |
| Database Link | |
| Background | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. provided by RefSeq, Jul 2008 |
| Synonyms | IMD18; T3E; TCRE |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Immune system diseases, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "UMAB54" antibodies (2)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| UM500048 | CD3E mouse monoclonal antibody,clone UMAB54 | 100 ul |
$610.00
|
|
| UM500048CF | Carrier-free (BSA/glycerol-free) CD3E mouse monoclonal antibody,clone UMAB54 | 100 ug |
$680.00
|
|
Citations
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