ALDH1L1 Mouse Monoclonal Antibody [Clone ID: UMAB43]
Specifications
| Product Data | |
| Clone Name | UMAB43 |
|---|---|
| Application | IF, IHC, WB |
| Recommended Dilution | WB 1:500, IHC 1:400, IF 1:100 |
| Reactivity | Dog, Human, Monkey, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human ALDH1L1 (NP_036322) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 98.6 kDa |
| Gene Name | aldehyde dehydrogenase 1 family member L1 |
| Database Link | |
| Background | The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jun 2012 |
| Synonyms | 10-fTHF; 10-FTHFDH; FDH; FTHFD |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | One carbon pool by folate |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "UMAB43" antibodies (2)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| UM500039 | ALDH1L1 mouse monoclonal antibody, clone UMAB43 | 100 ul |
$610.00
|
|
| UM500039CF | Carrier-free (BSA/glycerol-free) ALDH1L1 mouse monoclonal antibody, clone UMAB43 | 100 ug |
$680.00
|
|
Citations
Comprehensive mapping of Neurofibromin (NF1) expression in developing mouse brain
Lolam, Roy
Brain Struct Funct (2026) 231 (7) DOI: 10.1007/s00429-026-03173-x
Lolam, Roy
Brain Struct Funct (2026) 231 (7) DOI: 10.1007/s00429-026-03173-x
AI Summary: OriGene’s ALDH1L1 mouse monoclonal antibody (clone UMAB43, Cat # UM500039) was used in this study to label specific cell populations during immunohistochemistry, aiding in the detailed mapping of NF1 expression in the developing mouse brain.
Snippet: Antibody ALDH1L1 mouse monoclonal antibody, clone UMAB43 OriGene Origene (Cat # UM500039, RRID: AB_2629053)
Comprehensive mapping of Neurofibromin 1 (NF1) expression in developing mouse brain
Lolam, Roy
bioRxiv (2026)
Lolam, Roy
bioRxiv (2026)
Brainstem Neurotransmitter System Deterioration in Parkinson's Disease and Parkinson's Disease with Dementia
Huynh
Thesis (2023)
Huynh
Thesis (2023)
Snippet: Parkinson's disease (PD) is a progressive neurodegenerative disorder, characterised by motor symptoms due to the loss of nigral dopaminergic neurons and additional Save;Anti-ALDH1L1 (Mouse, monoclonal) OriGene, UM500039 1:200 Citraconic Anhydride ImmPRESS HRP Anti-Ms IgG Vector, MP-7402 Original solution
Anterograde transneuronal tracing and genetic control with engineered yellow fever vaccine YFV-17D
Li, Guo, Oh et al
Nat Methods (2021) 18 (12), 1542-1551 DOI: 10.1038/s41592-021-01319-9
Li, Guo, Oh et al
Nat Methods (2021) 18 (12), 1542-1551 DOI: 10.1038/s41592-021-01319-9
Cited by 45
AI Summary: In this study, the OriGene ALDH1L1 antibody (Clone: UMAB43, Cat# UM570039) was used at a 1:200 dilution to label and identify specific cell types, thereby supporting the validation of neuronal targeting and tracing achieved with the engineered YFV-17D viral system.
Snippet: Transneuronal viruses are powerful tools for tracing neuronal circuits or delivering genes to specific neurons in the brain. While there are multiple retrograde viruses, few anterograde viruses are available. Further, available anterograde viruses often have Save;ALDH1L1 antibody (Clone: UMAB43), Origene UM570039, 1:200
Targeting Mitochondrial Oxidative Phosphorylation Abrogated Irinotecan Resistance in NSCLC
Lee, Lee, Seo et al
Sci Rep (2018) 8 (1), 15707 DOI: 10.1038/s41598-018-33667-6
Lee, Lee, Seo et al
Sci Rep (2018) 8 (1), 15707 DOI: 10.1038/s41598-018-33667-6
AI Summary: In this study, the OriGene ALDH1L1 antibody (UM500039) was used to detect ALDH1L1 protein expression, helping to investigate the role of oxidative phosphorylation in irinotecan resistance in NSCLC cells.
Snippet: The primary antibodies used in the experiments were ALDH1L1 (UM500039, OriGene, Rockville, MD, USA), β-actin (sc-47778, Santa Cruz, Dallas, TX, USA) and OxPhos cocktail (ab110411, Abcam, Cambridge, UK). XF Cell Mito Stress Analysis;
Showing 1-5 of 5 papers.
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