CD19 Mouse Monoclonal Antibody [Clone ID: UMAB103]
$680.00
3 Days*
Specifications
| Product Data | |
| Clone Name | UMAB103 |
|---|---|
| Application | FC, IHC, WB |
| Recommended Dilution | IHC 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human CD19(NP_001761) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 60.9 kDa |
| Gene Name | CD19 molecule |
| Database Link | |
| Background | Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. provided by RefSeq, Jul 2008 |
| Synonyms | B4; CVID3 |
| Note | This antibody is the same clone with TA506236. |
| Reference Data | |
| Protein Categories | ADC Targets, CAR-T Targets, CD Markers, Immune system diseases, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | B cell receptor signaling pathway, Hematopoietic cell lineage, Primary immunodeficiency |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Citations
In vivo engineering of T cells with a synthetic cytokine receptor enables selective enrichment and expansion of anti-CD22 CAR T cells
Friesen, Sheih, Perdue et al
Mol Ther (2026)
Friesen, Sheih, Perdue et al
Mol Ther (2026)
Novel antibodies for identification, selection, and manipulation of T cells expressing Whitlow linker-containing CARs
Kimble, Wright, Torkelson et al
J Immunother Cancer (2025) 13 (11) DOI: 10.1136/jitc-2025-013123
Kimble, Wright, Torkelson et al
J Immunother Cancer (2025) 13 (11) DOI: 10.1136/jitc-2025-013123
Cited by 2
AI Summary: OriGene’s purified anti-CD19 monoclonal antibody (Cat# UM500071) was used as a comparator in immunohistochemistry experiments to evaluate the detection capabilities of newly developed anti-Whitlow antibodies for identifying CAR T cells in tissue samples.
Snippet: and baked at 60°C for 1 hour. For single-marker IHC, antigen retrieval was performed using Tris-EDTA buffer, pH 9 (Abcam, Cat# ab93684), at 95°C for 20 min. Purified anti-Whitlow or anti-CD19 (Origene #UM500071) mAbs were applied using an intelliPATH Stainer (Biocare Medical), followed by anti-mouse Fc secondary detection, visualization with 3,3′-diaminobenzidine chromogen, and hematoxyli
Compromised antigen binding and signaling interfere with bispecific CD19 and CD79a chimeric antigen receptor function
Leung, Templeton, Lo et al
Blood Adv (2022) 7 (12), 2718-2730 DOI: 10.1182/bloodadvances.2022008559
Leung, Templeton, Lo et al
Blood Adv (2022) 7 (12), 2718-2730 DOI: 10.1182/bloodadvances.2022008559
Cited by 27
AI Summary: OriGene contributed to this study by providing the CD19 antibody (UMAB103, UM500071), which was used for immunohistochemistry to assess antigen expression in lymphoma samples.
Snippet: POSITION ANTIBODY CLONE/HOST COMPANY/ITEM CONCENTRATION ΜG/ML OPAL FLUOR 1 CD3 SP7 / rabbit Thermo Fisher Scientific / RM-9107 0.06 (1:400) 520 2 CD19 UMAB103 / mouse Origene / UM500071 0.5 (1:2000) 690 3 CD33 RBT-CD33 / rabbit Bio SB Inc / BSB3451 1 (1:100) 570 4 CD79A JCB117 / mouse Bio SB Inc / BSB5305 0.166 (1:600) 540 5 CD79B;1 CD3 SP7 / Rabbit Thermo / RM-9107 0.06ug/ml (1:400) 520 2 CD19 UMAB103 / Mouse Origene / UM500071 0.5ug/ml (1:2k) 690 3 CD33 RBT-CD33 / Rabbit Bio SB / BSB3451 1ug/ml (1:100) 570 4 CD79A JCB117 / Mouse Bio SB / BSB5305 0.166ug/ml (1:600) 540 5 CD79B EPR6861 / Rabbit Abcam / ab134147 0.065 (1:1600) 620
A CAR RNA FISH assay to study functional and spatial heterogeneity of chimeric antigen receptor T cells in tissue
Eichholz, Li, Diem et al
Sci Rep (2021) 11 (1), 12921 DOI: 10.1038/s41598-021-92196-x
Eichholz, Li, Diem et al
Sci Rep (2021) 11 (1), 12921 DOI: 10.1038/s41598-021-92196-x
Cited by 7
AI Summary: OriGene’s mouse anti-huCD19 antibody (Clone ID: UMAB103) was used to stain tumor cells, enabling the identification and spatial analysis of tumor targets in the CAR RNA FISH assay described in the study.
Snippet: followed by incubation with the mouse antihuCD19 antibody to stain tumor cells (dilution 1:100,Clone ID: UMAB103, Origene) overnight at 4 °C
Showing 1-4 of 4 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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