CD31 (PECAM1) Mouse Monoclonal Antibody [Clone ID: UMAB29]
Specifications
| Product Data | |
| Clone Name | UMAB29 |
|---|---|
| Application | 10k-ChIP, FC, IF, IHC, WB |
| Recommended Dilution | WB 1:500, IHC 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human PECAM1(NP_000433) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 82.4 kDa |
| Gene Name | platelet and endothelial cell adhesion molecule 1 |
| Database Link | |
| Background | The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. provided by RefSeq |
| Synonyms | CD31; CD31/EndoCAM; endoCAM; GPIIA'; PECA1; PECAM-1 |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Citations
Durand, Ait-Aissa, Levchenko et al
Cardiovasc. Res. (2018)
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