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PSMA (FOLH1) Mouse Monoclonal Antibody [Clone ID: UMAB25]

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SKU
UM500025
FOLH1 mouse monoclonal antibody,clone UMAB25
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated
  $610.00
In Stock*
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View other "PSMA or NM_004476" antibodies

Specifications
Specifications
Product Data
Clone Name UMAB25
Application 10k-ChIP, IF, IHC, WB
Recommended Dilution WB 1:500~2000, IF 1:100, IF 1:100
Reactivity Dog, Human, Monkey, Mouse, Rat
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human FOLH1(NP_004467) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 84.2 kDa
Gene Name folate hydrolase 1
Database Link
Background This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. provided by RefSeq
Synonyms FGCP; FOLH; GCP2; GCPII; mGCP; NAALAD1; NAALAdase; PSM; PSMA
Reference Data
Protein Categories ADC Targets, CAR-T Targets, Enzyme: Peptidases, Intracellular Proteins, Membrane Proteins, Secreated Proteins
Protein Families Druggable Genome, Protease, Transmembrane
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Other "UMAB25" antibodies (2)
SKU Description Size Price
UM500025CF Carrier-free (BSA/glycerol-free) FOLH1 mouse monoclonal antibody,clone UMAB25 100 ug
$680.00
UM570025 FOLH1 mouse monoclonal antibody,clone UMAB25 30 ul
$224.00

file-alt Citations

Evaluating the transcriptional fidelity of cancer models
Peng, Gleyzer, Tai et al
Genome Med (2021) 13 (1), 73 DOI: 10.1186/s13073-021-00888-w
Cited by 51
AI Summary: In the paper "Evaluating the transcriptional fidelity of cancer models," OriGene’s RPL13A (Cat# TA505326) and TUBB (Cat# TA806828) antibodies were used for immunofluorescence validation of model predictions, contributing to the experimental confirmation of CancerCellNet’s computational assessments.
FigureFigureFigure
Evaluating the transcriptional fidelity of cancer models
Peng, Gleyzer, Tai et al
bioRxiv (2020)
Cited by 5
Snippet: …Cells were incubated with primary antibodies to goat HOXB6 (10 µg/mL, PA5-37867, Invitrogen), mouse WT1(10 µg/mL, MA1-46028, Invitrogen), rabbit PPARG (1:50, ABN1445, Millipore), mouse FOLH1(10 µg/mL, UM570025, Origene), and rabbit LIN28A (1:50, #3978, Cell Signaling) in Antibody Diluent (S080981-2, DAKO), at 4□°C overnight followed with three 5 min washes in TBST. …
ICC IF
Showing 1-2 of 2 papers.
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