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XPF (ERCC4) Mouse Monoclonal Antibody [Clone ID: UMAB21]

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SKU
UM500021CF
Carrier-free (BSA/glycerol-free) XPF mouse monoclonal antibody,clone UMAB21
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $680.00
3 Days*
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Specifications
Specifications
Product Data
Clone Name UMAB21
Application 10k-ChIP, IF, IHC, WB
Recommended Dilution WB 1:200~500, IF 1:100, FLOW 1:100, IHC 1:500
Reactivity Dog, Human, Monkey, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human XPF (NP_005227) produced in HEK293 cell.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 104.3 kDa
Gene Name ERCC excision repair 4, endonuclease catalytic subunit
Database Link
Background The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).
Synonyms ERCC11; FANCQ; RAD1; XFEPS; XPF
Reference Data
Protein Categories Cardiovascular diseases, Intracellular Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome
Protein Pathways Nucleotide excision repair
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Other "UMAB21" antibodies (2)
SKU Description Size Price
UM500021 XPF mouse monoclonal antibody,clone UMAB21 100 ul
$610.00
UM570021 XPF mouse monoclonal antibody,clone UMAB21 30 ul
$224.00

file-alt Citations

TGF beta promotes repair of bulky DNA damage through increased ERCC1/XPF and ERCC1/XPA interaction
Zheng, Jarvis, Bottai et al
Carcinogenesis (2018)
AI Summary: In this study, OriGene's anti-XPF mouse monoclonal antibody (clone UMAB21, UM500021) was used to detect XPF protein and analyze its interaction and localization in response to TGFβ treatment, contributing to findings on DNA repair mechanisms.
Snippet: 28353) were from Santa Cruz Biotechnology (Santa Cruz, CA,). Anti-XPF mouse monoclonal antibody (clone UMAB21, UM500021) was purchased from OriGene Technologies (Rockville, MD,). The concentrations of antibodies were 1:100. Anti-γH2AX (Ser139)
Showing 1-1 of 1 papers.
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