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GLCNE (GNE) Rabbit Polyclonal Antibody

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SKU
TA890043
Rabbit polyclonal anti-GNE Antibody
Size:
100 ul 30 ul
Conjugation:
Unconjugated
  $407.00
In Stock*
Bulk/Customize

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View other "GLCNE or NM_005476" antibodies

Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB: 1:500~1:1000
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant protein of human GNE
Buffer PBS (pH 7.3) containing 50% glycerol and 0.02% sodium azide
Concentration 4.29mg/ml
Purification Purified from the immunized serum by affinity chromatography (Protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 79.1 kDa
Gene Name glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Database Link
Background The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. provided by RefSeq, Jul 2008
Synonyms DMRV; GLCNE; IBM2; NM; Uae1
Reference Data
Protein Categories Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome
Protein Pathways Amino sugar and nucleotide sugar metabolism, Metabolic pathways
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Other antibodies (1)
SKU Description Size Price
TA890043S Rabbit polyclonal anti-GNE Antibody 30 ul
$188.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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