MADH7 (SMAD7) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB: 1:500~1:1000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human SMAD7 |
| Buffer | PBS (pH 7.3) containing 50% glycerol and 0.02% sodium azide |
| Concentration | 2.57mg/ml |
| Purification | Purified from the immunized serum by affinity chromatography (Protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 46.2 kDa |
| Gene Name | SMAD family member 7 |
| Database Link | |
| Background | The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jun 2010 |
| Synonyms | CRCS3; MADH7; MADH8 |
| Reference Data | |
| Protein Categories | Cancer: Gastrointestinal, Cytokines, Growth Factors, Intracellular Proteins, Transciption Factors |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | TGF-beta signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other antibodies (1)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA890026S | Rabbit polyclonal anti-SMAD7 Antibody | 30 ul |
$188.00
|
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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