Calcium Sensing Receptor (CASR) Rabbit Polyclonal Antibody

SKU
TA890014
Rabbit polyclonal anti-CASR Antibody
  $407.00
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Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB: 1:500
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant protein of human CASR
Buffer PBS (pH 7.3) containing 50% glycerol and 0.02% sodium azide
Concentration 2.22mg/ml
Purification Purified from the immunized serum by affinity chromatography (Protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 120.5 kDa
Gene Name calcium sensing receptor
Database Link
Background The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. provided by RefSeq, Jul 2008
Synonyms CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1
Reference Data
Protein Categories Cancer: Endocrine, Endocrine and metabolic diseases, GPCR, Growth Factors, Membrane Proteins, Nervous system Diseases
Protein Families Druggable Genome, GPCR, Transmembrane
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SKU Description Size Price
TA890014S Rabbit polyclonal anti-CASR Antibody 30 ul
$188.00

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