RUNX2 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3E12]
$509.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | OTI3E12 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:1000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1-293 of human RUNX2 (NP_004339) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA and 50% glycerol |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | HRP |
| Storage | Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 54.9 kDa |
| Gene Name | runt related transcription factor 2 |
| Database Link | |
| Background | This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. provided by RefSeq, Jul 2016 |
| Synonyms | AML3; CBFA1; CCD; CCD1; OSF-2; OSF2; PEA2aA; PEBP2A1; PEBP2A2; PEBP2aA; PEBP2aA1 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins, Transciption Factors |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3E12" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF813668 | Carrier-free (BSA/glycerol-free) RUNX2 mouse monoclonal antibody, clone OTI3E12 | 100 ug |
$620.00
|
|
| TA813668 | RUNX2 mouse monoclonal antibody, clone OTI3E12 | 100 ul |
$447.00
|
|
| TA813668AM | RUNX2 mouse monoclonal antibody, clone OTI3E12, Biotinylated | 100 ul |
$509.00
|
|
| TA813668S | RUNX2 mouse monoclonal antibody, clone OTI3E12 | 30 ul |
$200.00
|
|
Citations
Methylation and expression of RECK, P53 and RUNX genes in patients with esophageal cancer
Lu, Zabihula, Yibulayin et al
Oncol Lett (2017) 14 (5), 5293-5298 DOI: 10.3892/ol.2017.6863
Lu, Zabihula, Yibulayin et al
Oncol Lett (2017) 14 (5), 5293-5298 DOI: 10.3892/ol.2017.6863
Cited by 11
AI Summary: OriGene products, specifically the RECK (NM_021111) Human cDNA Clone, P53 (NM_000546) Human cDNA Clone, and RUNX (NM_001754) Human cDNA Clone, were used as positive controls in RT-qPCR experiments to measure the mRNA expression levels of RECK, P53, and RUNX genes in patients with esophageal cancer and healthy controls.
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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