HLAA (HLA-A) Mouse Monoclonal Antibody [Clone ID: OTI4D11]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI4D11 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:500-1000 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 25-308 of human HLA-A (NP_002107) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 40.8 kDa |
| Gene Name | major histocompatibility complex, class I, A |
| Database Link | |
| Background | HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. provided by RefSeq, Jul 2008. |
| Synonyms | HLAA |
| Reference Data | |
| Protein Categories | Cytokines, Intracellular Proteins, Membrane Proteins |
| Protein Families | Transmembrane |
| Protein Pathways | Allograft rejection, Antigen processing and presentation, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Endocytosis, Graft-versus-host disease, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus, Viral myocarditis |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI4D11" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF813375 | Carrier-free (BSA/glycerol-free) HLA mouse monoclonal antibody, clone OTI4D11 | 100 ug |
$620.00
|
|
| TA813375AM | HLA mouse monoclonal antibody, clone OTI4D11, Biotinylated | 100 ul |
$509.00
|
|
| TA813375BM | HLA mouse monoclonal antibody, clone OTI4D11, HRP conjugated | 100 ul |
$509.00
|
|
| TA813375S | HLA mouse monoclonal antibody, clone OTI4D11 | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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