DUSP1 Mouse Monoclonal Antibody [Clone ID: OTI5A8]
$200.00
2 Days*
Specifications
| Product Data | |
| Clone Name | OTI5A8 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:500 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human DUSP1 (NP_004408) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 39.1 kDa |
| Gene Name | dual specificity phosphatase 1 |
| Database Link | |
| Background | The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. provided by RefSeq, Jul 2008 |
| Synonyms | CL100; HVH1; MKP-1; MKP1; PTPN10 |
| Reference Data | |
| Protein Categories | Chemokines, Intracellular Proteins |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | MAPK signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI5A8" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF812681 | Carrier-free (BSA/glycerol-free) DUSP1 mouse monoclonal antibody,clone OTI5A8 | 100 ug |
$620.00
|
|
| TA812681 | DUSP1 mouse monoclonal antibody,clone OTI5A8 | 100 ul |
$447.00
|
|
| TA812681AM | DUSP1 mouse monoclonal antibody,clone OTI5A8, Biotinylated | 100 ul |
$509.00
|
|
| TA812681BM | DUSP1 mouse monoclonal antibody,clone OTI5A8, HRP conjugated | 100 ul |
$509.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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