IL15RA Mouse Monoclonal Antibody [Clone ID: OTI7F4]
Specifications
| Product Data | |
| Clone Name | OTI7F4 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:500 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 31-267 of human IL15RA (NP_001230468) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 28.22 kDa |
| Gene Name | interleukin 15 receptor subunit alpha |
| Database Link | |
| Background | This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported. provided by RefSeq, Apr 2010 |
| Synonyms | CD215 |
| Reference Data | |
| Protein Categories | CD Markers, Cytokines, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI7F4" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF812233 | Carrier-free (BSA/glycerol-free) IL15RA mouse monoclonal antibody,clone OTI7F4 | 100 ug |
$620.00
|
|
| TA812233AM | IL15RA mouse monoclonal antibody,clone OTI7F4, Biotinylated | 100 ul |
$509.00
|
|
| TA812233BM | IL15RA mouse monoclonal antibody,clone OTI7F4, HRP conjugated | 100 ul |
$509.00
|
|
| TA812233S | IL15RA mouse monoclonal antibody,clone OTI7F4 | 30 ul |
$200.00
|
|
Citations
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