MRC2 Mouse Monoclonal Antibody [Clone ID: OTI9G4]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI9G4 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:500~2000, IHC 1:5000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human MRC2 (NP_006030) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 166.5 kDa |
| Gene Name | mannose receptor C type 2 |
| Database Link | |
| Background | This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. provided by RefSeq, Feb 2012 |
| Synonyms | CD280; CLEC13E; ENDO180; UPARAP |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI9G4" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF811858 | Carrier-free (BSA/glycerol-free) MRC2 mouse monoclonal antibody,clone OTI9G4 | 100 ug |
$620.00
|
|
| TA811858AM | MRC2 mouse monoclonal antibody,clone OTI9G4, Biotinylated | 100 ul |
$509.00
|
|
| TA811858BM | MRC2 mouse monoclonal antibody,clone OTI9G4, HRP conjugated | 100 ul |
$509.00
|
|
| TA811858S | MRC2 mouse monoclonal antibody,clone OTI9G4 | 30 ul |
$200.00
|
|
Citations
Molecular epidemiology of the expression of urokinase plasminogen activator receptor-associated protein (uPARAP) in mesenchymal malignancies
Wang, Barkholt, Wozniak et al
Transl Oncol (2026) 66, 102708 DOI: 10.1016/j.tranon.2026.102708
Wang, Barkholt, Wozniak et al
Transl Oncol (2026) 66, 102708 DOI: 10.1016/j.tranon.2026.102708
Architectural organization and molecular profiling of 3D cancer heterospheroids and their application in drug testing
Nielsen, Madsen, Larsen et al
Front Oncol (2024) 14, 1386097 DOI: 10.3389/fonc.2024.1386097
Nielsen, Madsen, Larsen et al
Front Oncol (2024) 14, 1386097 DOI: 10.3389/fonc.2024.1386097
Cited by 7
AI Summary: OriGene contributed to this study by providing the Mouse anti-Mannose Receptor C Type 2 (MRC2, CD280, mAb OTI9G4) antibody, which was used for immunohistochemical analysis to characterize the cellular composition and organization of the 3D cancer heterospheroids.
Snippet: b anti-collagen-1 diluted 1:3,000 (RabMab EPR7785) were all obtained from AbCam, Cambridge, UK. Mouse (Ms) anti-Mannose Receptor C Type 2 (MRC2, CD280, mAb OTI9G4), diluted 1:10,000 was obtained from OriGene, Rockville MD, USA, and Ms anti-pan cytokeratin (CK, mAb MNF116, M0821) diluted 1:1,000 was obtained from Dako-Agilent, Glostrup, Denmark. The primary antibodies were detected using horse-radi
The Collagen Receptor uPARAP in Malignant Mesothelioma: A Potential Diagnostic Marker and Therapeutic Target
Çakılkaya, Sørensen, Jürgensen et al
Int J Mol Sci (2021) 22 (21) DOI: 10.3390/ijms222111452
Çakılkaya, Sørensen, Jürgensen et al
Int J Mol Sci (2021) 22 (21) DOI: 10.3390/ijms222111452
Cited by 10
AI Summary: OriGene products, specifically the anti-uPARAP antibody (Cat# TA326500) and the uPARAP cDNA clone (Cat# RC208482), were used in this study to detect and analyze uPARAP expression in malignant mesothelioma tissues and cell lines, contributing to the identification of uPARAP as a potential diagnostic marker and therapeutic target.
Showing 1-3 of 3 papers.
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