GTP cyclohydrolase 1 (GCH1) Mouse Monoclonal Antibody [Clone ID: OTI5A1]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI5A1 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:500 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human GCH1 (NP_001019195) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 27.7 kDa |
| Gene Name | GTP cyclohydrolase 1 |
| Database Link | |
| Background | This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. provided by RefSeq, Jul 2008 |
| Synonyms | DYT5; DYT5a; DYT14; GCH; GTP-CH-1; GTPCH1; HPABH4B |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome |
| Protein Pathways | Folate biosynthesis, Metabolic pathways |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI5A1" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF810265 | Carrier-free (BSA/glycerol-free) GCH1 mouse monoclonal antibody,clone OTI5A1 | 100 ug |
$620.00
|
|
| TA810265AM | GCH1 mouse monoclonal antibody,clone OTI5A1, Biotinylated | 100 ul |
$509.00
|
|
| TA810265BM | GCH1 mouse monoclonal antibody,clone OTI5A1, HRP conjugated | 100 ul |
$509.00
|
|
| TA810265S | GCH1 mouse monoclonal antibody,clone OTI5A1 | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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