CD160 Mouse Monoclonal Antibody [Clone ID: OTI2G2]

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SKU
TA809703
CD160 mouse monoclonal antibody,clone OTI2G2
  $447.00
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Specifications
Specifications
Product Data
Clone Name OTI2G2
Application WB
Recommended Dilution WB 1:2000
Reactivity Human
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-160 of human CD160 (NP_008984) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name CD160 molecule
Database Link
Background CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. provided by RefSeq, Jul 2008
Synonyms BY55; NK1; NK28
Reference Data
Protein Categories CD Markers, Cytokines, Secreated Proteins
Protein Families Druggable Genome
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SKU Description Size Price
CF809703 Carrier-free (BSA/glycerol-free) CD160 mouse monoclonal antibody,clone OTI2G2 100 ug
$620.00

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