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DIRAS2 Mouse Monoclonal Antibody [Clone ID: OTI8A5]

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SKU
TA809398
DIRAS2 mouse monoclonal antibody,clone OTI8A5
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
Bulk/Customize

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View other "DIRAS2 or NM_017594" antibodies

Specifications
Specifications
Product Data
Clone Name OTI8A5
Application IHC, WB
Recommended Dilution WB 1:500~2000, IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-196 of human DIRAS2(NP_060064) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 22.3 kDa
Gene Name DIRAS family GTPase 2
Database Link
Background DIRAS2 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases. supplied by OMIM, Apr 2004. ##Evidence-Data-START## Transcript exon combination :: AK122986.1, BC008065.2 ECO:0000332 RNAseq introns :: single sample supports all introns ERS025084, ERS025085 ECO:0000348 ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
Synonyms Di-Ras2
Reference Data
Protein Categories Intracellular Proteins
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Other "OTI8A5" antibodies (4)
SKU Description Size Price
CF809398 Carrier-free (BSA/glycerol-free) DIRAS2 mouse monoclonal antibody,clone OTI8A5 100 ug
$620.00
TA809398AM DIRAS2 mouse monoclonal antibody,clone OTI8A5, Biotinylated 100 ul
$509.00
TA809398BM DIRAS2 mouse monoclonal antibody,clone OTI8A5, HRP conjugated 100 ul
$509.00
TA809398S DIRAS2 mouse monoclonal antibody,clone OTI8A5 30 ul
$200.00

file-alt Citations

The small GTP-binding Ras-like protein DIRAS2 promotes cell proliferation in oral leukoplakia via the RAF/MEK/MAPK pathway
Li, Tian, Li et al
Tissue Cell (2025) 96, 103037 DOI: 10.1016/j.tice.2025.103037
Cited by 4
AI Summary: OriGene's anti-DIRAS2 antibody was used in this study to detect DIRAS2 protein expression, contributing to the investigation of its role in promoting cell proliferation in oral leukoplakia via the RAF/MEK/MAPK pathway.
Snippet: Membranes were then blocked with 5 % skim milk and incubated overnight at 4 °C with antibodies against the target proteins as follows: anti-DIRAS2 (1:10000, Origene, China), anti-PCNA (1:1000, Proteintech, China), anti-p-MEK1/2 (1:1000, Proteintech, China), and anti-p-ERK (1:1000, CST, USA). …
WB
DIRAS2 Contributes to Radiation Resistance of Renal Cell Carcinoma Via Autophagy Induction and MKK4-JNK1 Pathway Activation
Cai, He, Yue et al
Research Square (2022)
Snippet: Subsequently, slices were incubated with a mouse polyclonal DIRAS2 antibody (Origene, TA809398), diluted in 1% goat serum (1:500) at 4 C overnight. After incubated with horseradish peroxidase (HRP)-conjugated secondary antibody for 1h at room temperature
IHC
RAS-related GTPases DIRAS1 and DIRAS2 induce autophagic cancer cell death and are required for autophagy in murine ovarian cancer cells
Sutton, Yang, Huang et al
Autophagy (2018)
AI Summary: In this study, OriGene products—including the anti-DIRAS2 antibody (TA809398) and pCMV-DIRAS1 and pCMV-DIRAS2 mouse and human plasmids (SC100097)—were used to detect DIRAS2 protein expression and to re-express DIRAS1 and DIRAS2 in cancer cells, enabling the investigation of their roles in autophagy and cancer cell death.
Snippet: other members of the DIRAS family. Antibody against DIRAS2 (TA 809398) was purchased from Origene. AKT (sc-514302) and MAPK/ERK (sc-514302) antibodies pCMV-DIRAS1 and pCMV- DIRAS2 mouse and human plasmids were purchased from Origene (SC100097
Showing 1-3 of 3 papers.
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