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BLNK Mouse Monoclonal Antibody [Clone ID: OTI2B2]

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SKU
TA808522
BLNK mouse monoclonal antibody, clone OTI2B2 (formerly 2B2)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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View other "BLNK or NM_013314" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2B2
Application WB
Recommended Dilution WB 1:2000
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-292 of human BLNK(NP_037446) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 50.3 kDa
Gene Name B-cell linker
Database Link
Background This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, May 2012
Synonyms AGM4; BASH; bca; BLNK-S; LY57; SLP-65; SLP65
Reference Data
Protein Categories Immune system diseases, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways B cell receptor signaling pathway, Primary immunodeficiency
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Other "OTI2B2" antibodies (4)
SKU Description Size Price
CF808522 Carrier-free (BSA/glycerol-free) BLNK mouse monoclonal antibody, clone OTI2B2 (formerly 2B2) 100 ug
$620.00
TA808522AM BLNK mouse monoclonal antibody, clone OTI2B2 (formerly 2B2), Biotinylated 100 ul
$509.00
TA808522BM BLNK mouse monoclonal antibody, clone OTI2B2 (formerly 2B2), HRP conjugated 100 ul
$509.00
TA808522S BLNK mouse monoclonal antibody, clone OTI2B2 (formerly 2B2) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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