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MAP3K8 Mouse Monoclonal Antibody [Clone ID: OTI2E3]

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SKU
TA808459
MAP3K8 mouse monoclonal antibody,clone OTI2E3
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
Bulk/Customize

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View other "MAP3K8 or NM_005204" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2E3
Application IHC, WB
Recommended Dilution WB 1:500, IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 277-461 of human MAP3K8(NP_005195) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 52.7 kDa
Gene Name mitogen-activated protein kinase kinase kinase 8
Database Link
Background This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. provided by RefSeq, Sep 2011
Synonyms AURA2; c-COT; COT; EST; ESTF; MEKK8; Tpl-2; TPL2
Reference Data
Protein Categories Enzyme: Kinases, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase
Protein Pathways MAPK signaling pathway, T cell receptor signaling pathway, Toll-like receptor signaling pathway
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Other "OTI2E3" antibodies (4)
SKU Description Size Price
CF808459 Carrier-free (BSA/glycerol-free) MAP3K8 mouse monoclonal antibody,clone OTI2E3 100 ug
$620.00
TA808459AM MAP3K8 mouse monoclonal antibody,clone OTI2E3, Biotinylated 100 ul
$509.00
TA808459BM MAP3K8 mouse monoclonal antibody,clone OTI2E3, HRP conjugated 100 ul
$509.00
TA808459S MAP3K8 mouse monoclonal antibody,clone OTI2E3 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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