PIAS2 Mouse Monoclonal Antibody [Clone ID: OTI5B4]
Specifications
| Product Data | |
| Clone Name | OTI5B4 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:500 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human PIAS2(NP_004662) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 68.1 kDa |
| Gene Name | protein inhibitor of activated STAT 2 |
| Database Link | |
| Background | This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. provided by RefSeq, Aug 2011 |
| Synonyms | ARIP3; DIP; MIZ; MIZ1; PIASX; PIASX-ALPHA; PIASX-BETA; SIZ2; ZMIZ4 |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Membrane Proteins |
| Protein Families | Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors |
| Protein Pathways | Jak-STAT signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI5B4" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF808334 | Carrier-free (BSA/glycerol-free) PIAS2 mouse monoclonal antibody, clone OTI5B4 | 100 ug |
$620.00
|
|
| TA808334AM | PIAS2 mouse monoclonal antibody,clone OTI5B4, Biotinylated | 100 ul |
$509.00
|
|
| TA808334BM | PIAS2 mouse monoclonal antibody,clone OTI5B4, HRP conjugated | 100 ul |
$509.00
|
|
| TA808334S | PIAS2 mouse monoclonal antibody,clone OTI5B4 | 30 ul |
$200.00
|
|
Citations
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