IL12A Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2A8]
Specifications
| Product Data | |
| Clone Name | OTI2A8 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:500 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 57-253 of human IL12A(NP_000873) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA and 50% glycerol |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | HRP |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | interleukin 12A |
| Database Link | |
| Background | This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. provided by RefSeq, Jul 2008 |
| Synonyms | CLMF; IL-12A; NFSK; NKSF1; P35 |
| Reference Data | |
| Protein Categories | Cytokines, Growth Factors, Intracellular Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Allograft rejection, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Type I diabetes mellitus |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2A8" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF808081 | Carrier-free (BSA/glycerol-free) IL12A mouse monoclonal antibody, clone OTI2A8 (formerly 2A8) | 100 ug |
$620.00
|
|
| TA808081 | IL12A mouse monoclonal antibody, clone OTI2A8 (formerly 2A8) | 100 ul |
$447.00
|
|
| TA808081AM | IL12A mouse monoclonal antibody, clone OTI2A8 (formerly 2A8), Biotinylated | 100 ul |
$509.00
|
|
| TA808081S | IL12A mouse monoclonal antibody, clone OTI2A8 (formerly 2A8) | 30 ul |
$200.00
|
|
Citations
Dajnoki, Somogyi, Medgyesi et al
J Eur Acad Dermatol Venereol (2021)
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