IL12A Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2A8]

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SKU
TA808081BM
IL12A mouse monoclonal antibody, clone OTI2A8 (formerly 2A8), HRP conjugated
  $509.00
2 Weeks*
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Specifications
Specifications
Product Data
Clone Name OTI2A8
Application WB
Recommended Dilution WB 1:500
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 57-253 of human IL12A(NP_000873) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA and 50% glycerol
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name interleukin 12A
Database Link
Background This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. provided by RefSeq, Jul 2008
Synonyms CLMF; IL-12A; NFSK; NKSF1; P35
Reference Data
Protein Categories Cytokines, Growth Factors, Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Type I diabetes mellitus
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Other "OTI2A8" antibodies (4)
SKU Description Size Price
CF808081 Carrier-free (BSA/glycerol-free) IL12A mouse monoclonal antibody, clone OTI2A8 (formerly 2A8) 100 ug
$620.00
TA808081 IL12A mouse monoclonal antibody, clone OTI2A8 (formerly 2A8) 100 ul
$447.00
TA808081AM IL12A mouse monoclonal antibody, clone OTI2A8 (formerly 2A8), Biotinylated 100 ul
$509.00
TA808081S IL12A mouse monoclonal antibody, clone OTI2A8 (formerly 2A8) 30 ul
$200.00

file-alt Citations

Primary alterations during the development of hidradenitis suppurativa
Dajnoki, Somogyi, Medgyesi et al
J Eur Acad Dermatol Venereol (2021)
Cited by 48
AI Summary: In this study, the OriGene product "human CD163 (mouse monoclonal IgG [BM4041B])" was used to identify and quantify macrophages in skin samples, contributing to the analysis of immune cell involvement during different stages of hidradenitis suppurativa.
Snippet: …Save;- ), human TNF-α (mouse monoclonal IgG [SAB1404480-100UG]: SigmaAldrich), human CD4 (rabbit monoclonal IgG [ab133616]: Abcam), human CD11c (rabbit monoclonal IgG [ab52632]: Abcam), human CD163 (mouse monoclonal IgG [BM4041B]: Origene),
IHC IF
Showing 1-1 of 1 papers.
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