CD11b (ITGAM) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2D11]

SKU
TA807953AM
ITGAM mouse monoclonal antibody, clone OTI2D11 (formerly 2D11), Biotinylated
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    Antibodies made against full-length proteins as antigens.

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$509.00
2 Weeks*
Specifications
Product Data
Clone Name OTI2D11
Application IHC, WB
Recommended Dilution WB 1:500, IHC 1:150
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human ITGAM (NP_000623) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 125.4 kDa
Gene Name integrin subunit alpha M
Database Link
Background This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Synonyms CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Leukocyte transendothelial migration, Regulation of actin cytoskeleton
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SKU Description Size Price
CF807953 Carrier-free (BSA/glycerol-free) ITGAM mouse monoclonal antibody, clone OTI2D11 (formerly 2D11) 100 ug
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TA807953 ITGAM mouse monoclonal antibody, clone OTI2D11 (formerly 2D11) 100 ul
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TA807953BM ITGAM mouse monoclonal antibody, clone OTI2D11 (formerly 2D11), HRP conjugated 100 ul
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TA807953S ITGAM mouse monoclonal antibody, clone OTI2D11 (formerly 2D11) 30 ul
$200.00

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.