CD40 Mouse Monoclonal Antibody [Clone ID: OTI9F4]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI9F4 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 21-166 of human CD40(NP_001241) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 28.4 kDa |
| Gene Name | CD40 molecule |
| Database Link | |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul |
| Synonyms | Bp50; CDW40; p50; TNFRSF5 |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Immune system diseases, Membrane Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Cytokine-cytokine receptor interaction, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Viral myocarditis |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI9F4" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF807686 | Carrier-free (BSA/glycerol-free) CD40 mouse monoclonal antibody, clone OTI9F4 (formerly 9F4) | 100 ug |
$620.00
|
|
| TA807686AM | CD40 mouse monoclonal antibody, clone OTI9F4 (formerly 9F4), Biotinylated | 100 ul |
$509.00
|
|
| TA807686BM | CD40 mouse monoclonal antibody, clone OTI9F4 (formerly 9F4), HRP conjugated | 100 ul |
$509.00
|
|
| TA807686S | CD40 mouse monoclonal antibody, clone OTI9F4 (formerly 9F4) | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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