Granulin (GRN) Mouse Monoclonal Antibody [Clone ID: OTI3H6]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI3H6 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 327-593 of human GRN(NP_002078) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 61.7 kDa |
| Gene Name | granulin |
| Database Link | |
| Background | Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. provided by RefSeq, Jul 2008 |
| Synonyms | CLN11; GEP; GP88; PCDGF; PEPI; PGRN |
| Reference Data | |
| Protein Categories | Cytokines, Growth Factors, Intracellular Proteins, Nervous system: Neurodegenerative diseases, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3H6" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF807350 | Carrier-free (BSA/glycerol-free) GRN mouse monoclonal antibody, clone OTI3H6 | 100 ug |
$620.00
|
|
| TA807350AM | GRN mouse monoclonal antibody, clone OTI3H6, Biotinylated | 100 ul |
$509.00
|
|
| TA807350BM | GRN mouse monoclonal antibody, clone OTI3H6, HRP conjugated | 100 ul |
$509.00
|
|
| TA807350S | GRN mouse monoclonal antibody, clone OTI3H6 | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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