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RET Mouse Monoclonal Antibody [Clone ID: OTI5C5]

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SKU
TA805767
RET mouse monoclonal antibody, clone OTI5C5 (formerly 5C5)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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View other "RET or NM_020975" antibodies

Specifications
Specifications
Product Data
Clone Name OTI5C5
Application IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivity Human, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 713-1017 of human RET(NP_066124) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 124.1 kDa
Gene Name ret proto-oncogene
Database Link
Background This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. provided by RefSeq, Jul 2008
Synonyms CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET-ELE1; RET51
Reference Data
Protein Categories ADC Targets, Cancer: Endocrine, Cancer: Lung, Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Endocytosis, Pathways in cancer, Thyroid cancer
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Other "OTI5C5" antibodies (4)
SKU Description Size Price
CF805767 Carrier-free (BSA/glycerol-free) RET mouse monoclonal antibody, clone OTI5C5 (formerly 5C5) 100 ug
$620.00
TA805767AM RET mouse monoclonal antibody, clone OTI5C5 (formerly 5C5), Biotinylated 100 ul
$509.00
TA805767BM RET mouse monoclonal antibody, clone OTI5C5 (formerly 5C5), HRP conjugated 100 ul
$509.00
TA805767S RET mouse monoclonal antibody, clone OTI5C5 (formerly 5C5) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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