OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Constitutive androstane receptor (NR1I3) Mouse Monoclonal Antibody [Clone ID: OTI10F9]

  • Product Brand Image
Be the first to review this product
SKU
TA805306
NR1I3 mouse monoclonal antibody, clone OTI10F9 (formerly 10F9)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
Bulk/Customize

Frequently Bought Together (2)

TA811000S beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control 30 ul
$200.00
LY421424 Transient overexpression lysate of nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 6 (as WB positive control) 100 ug
$436.00

View other "Constitutive androstane receptor or NM_001077482" antibodies

Specifications
Specifications
Product Data
Clone Name OTI10F9
Application IHC
Recommended Dilution IHC 1:150
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-236 of human NR1I3 (NP_001070950) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 40.3 kDa
Gene Name nuclear receptor subfamily 1 group I member 3
Database Link
Background This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008
Synonyms CAR; CAR1; MB67
Reference Data
Protein Categories Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other "OTI10F9" antibodies (4)
SKU Description Size Price
CF805306 Carrier-free (BSA/glycerol-free) NR1I3 mouse monoclonal antibody, clone OTI10F9 (formerly 10F9) 100 ug
$620.00
TA805306AM NR1I3 mouse monoclonal antibody, clone OTI10F9 (formerly 10F9), Biotinylated 100 ul
$509.00
TA805306BM NR1I3 mouse monoclonal antibody, clone OTI10F9 (formerly 10F9), HRP conjugated 100 ul
$509.00
TA805306S NR1I3 mouse monoclonal antibody, clone OTI10F9 (formerly 10F9) 30 ul
$200.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products