EPOR Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4F12]
$509.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | OTI4F12 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 25-250 of human EPOR (NP_000112) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Biotin |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | erythropoietin receptor |
| Database Link | |
| Background | This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. provided by RefSeq, May 2010 |
| Synonyms | EPO-R |
| Reference Data | |
| Protein Categories | Cardiovascular diseases, Cytokines, Growth Factors, Membrane Proteins |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI4F12" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF804627 | Carrier-free (BSA/glycerol-free) EPOR mouse monoclonal antibody, clone OTI4F12 (formerly 4F12) | 100 ug |
$620.00
|
|
| TA804627 | EPOR mouse monoclonal antibody, clone OTI4F12 (formerly 4F12) | 100 ul |
$447.00
|
|
| TA804627BM | EPOR mouse monoclonal antibody, clone OTI4F12 (formerly 4F12), HRP conjugated | 100 ul |
$509.00
|
|
| TA804627S | EPOR mouse monoclonal antibody, clone OTI4F12 (formerly 4F12) | 30 ul |
$200.00
|
|
Citations
Erythropoietin receptor upregulation is associated with tubular injury severity in human acute kidney injury
Xie, Zhou, Li et al
Ren Fail (2026) 48 (1), 2650260-2650260 DOI: 10.1080/0886022x.2026.2650260
Xie, Zhou, Li et al
Ren Fail (2026) 48 (1), 2650260-2650260 DOI: 10.1080/0886022x.2026.2650260
AI Summary: OriGene’s anti-EPOR antibody (catalog # OTI4F12) was used to detect and quantify erythropoietin receptor expression in kidney tissue samples, enabling the study to link EPOR upregulation with the severity of tubular injury in human acute kidney injury.
Snippet: rried out for 30 min. Sections were then blocked with 3% bovine serum albumin (BSA) for 30 min and incubated overnight at 4 °C with the following primary antibodies: anti-EPOR (1:150 dilution, Origene, Rockville, MD, catalog # OTI4F12) and anti‑βcR (1:500 dilution, Servicebio, Wuhan, China, catalog #
Showing 1-1 of 1 papers.
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