ABCD1 Mouse Monoclonal Antibody [Clone ID: OTI4E2]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI4E2 |
|---|---|
| Application | IHC |
| Recommended Dilution | IHC 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 508-745 of human ABCD1 (NP_000024) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 82.8 kDa |
| Gene Name | ATP binding cassette subfamily D member 1 |
| Database Link | |
| Background | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. provided by RefSeq, Jul 2008 |
| Synonyms | ABC42; ALD; ALDP; AMN |
| Reference Data | |
| Protein Categories | Cytokines, Membrane Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | ABC transporters |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI4E2" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF803204 | Carrier-free (BSA/glycerol-free) ABCD1 mouse monoclonal antibody, clone OTI4E2 (formerly 4E2) | 100 ug |
$620.00
|
|
| TA803204AM | ABCD1 mouse monoclonal antibody,clone 4E2, Biotinylated | 100 ul |
$509.00
|
|
| TA803204BM | ABCD1 mouse monoclonal antibody,clone 4E2, HRP conjugated | 100 ul |
$509.00
|
|
| TA803204S | ABCD1 mouse monoclonal antibody, clone OTI4E2 (formerly 4E2) | 30 ul |
$200.00
|
|
Citations
Adenoassociated virus serotype 9-mediated gene therapy for x-linked adrenoleukodystrophy
Gong, Mu, Prabhakar et al
Mol Ther (2015) 23 (5), 824-834 DOI: 10.1038/mt.2015.6
Gong, Mu, Prabhakar et al
Mol Ther (2015) 23 (5), 824-834 DOI: 10.1038/mt.2015.6
Cited by 78
Showing 1-1 of 1 papers.
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