Thymidylate Synthase (TYMS) Mouse Monoclonal Antibody [Clone ID: OTI10F12]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI10F12 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human TYMS (NP_001062) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 35.5 kDa |
| Gene Name | thymidylate synthetase |
| Database Link | |
| Background | Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. provided by RefSeq, Jul 2008 |
| Synonyms | HST422; TMS; TS |
| Reference Data | |
| Protein Categories | Cytokines, Growth Factors, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, One carbon pool by folate, Pyrimidine metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI10F12" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF801551 | Carrier-free (BSA/glycerol-free) TYMS mouse monoclonal antibody, clone OTI10F12 (formerly 10F12) | 100 ug |
$620.00
|
|
| TA801551AM | TYMS mouse monoclonal antibody,clone 10F12, Biotinylated | 100 ul |
$509.00
|
|
| TA801551BM | TYMS mouse monoclonal antibody,clone 10F12, HRP conjugated | 100 ul |
$509.00
|
|
| TA801551S | TYMS mouse monoclonal antibody, clone OTI10F12 (formerly 10F12) | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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