Neurofilament (NEFL) Mouse Monoclonal Antibody [Clone ID: OTI3G2]

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SKU
TA801110S
NEFL mouse monoclonal antibody,clone OTI3G2
  $200.00
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Specifications
Specifications
Product Data
Clone Name OTI3G2
Application ELISA (indirect), IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-360 of human NEFL (NP_006149) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 61.3 kDa
Gene Name neurofilament, light polypeptide
Database Link
Background Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. provided by RefSeq, Oct 2008
Synonyms CMT1F; CMT2E; NF-L; NF68; NFL; PPP1R110
Reference Data
Protein Categories Growth Factors, Intracellular Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome, ES Cell Differentiation/IPS
Protein Pathways Amyotrophic lateral sclerosis (ALS)
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Other "OTI3G2" antibodies (4)
SKU Description Size Price
CF801110 Carrier-free (BSA/glycerol-free) NEFL mouse monoclonal antibody,clone OTI3G2 100 ug
$620.00
TA801110 NEFL mouse monoclonal antibody,clone OTI3G2 100 ul
$447.00
TA801110AM NEFL mouse monoclonal antibody,clone 3G2, Biotinylated 100 ul
$509.00
TA801110BM NEFL mouse monoclonal antibody,clone 3G2, HRP conjugated 100 ul
$509.00

file-alt Citations

Microglial A20 Protects the Brain from CD8 T-Cell-Mediated Immunopathology
Mohebiany, Ramphal, Karram et al
Cell Rep (2020) 30 (5), 1585-1597.e6 DOI: 10.1016/j.celrep.2019.12.097
Cited by 85
AI Summary: In this study, the Mouse anti-(medium) Neurofilament antibody (Clone NF-09, OriGene Cat# SM3068P) from OriGene was used to label neuronal structures, contributing to the analysis of neuroanatomical changes associated with microglial A20 deficiency.
Snippet: Skip to article;Mouse anti-(medium) Neurofilament (Clone NF-09) Acris Antibodies GmbH (now OriGene) Cat# SM3068P;RRID: AB_1005618 Mouse anti-NeuN (Clone A60) Chemicon/Merk Millipore Cat# MAB377;RRID: AB_2298772 Rabbit anti-NeuN-Alexafluor 488 (clone EPR12763) Abcam Cat# ab190195;RRID: AB_2716282 Rabbit anti-Parvalbumin (antiserum) Swant Code# PV27;RRID: AB_2631173
Showing 1-1 of 1 papers.
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