P Glycoprotein (ABCB1) Mouse Monoclonal Antibody [Clone ID: OTI5B3]

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SKU
TA801055S
ABCB1 (P Glycoprotein) mouse monoclonal antibody, clone OTI5B3 (formerly 5B3)
  $200.00
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Specifications
Specifications
Product Data
Clone Name OTI5B3
Application IHC, WB
Recommended Dilution IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 995-1280 of human ABCB1 (NP_000918) produced in SF9 cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name ATP binding cassette subfamily B member 1
Database Link
Background The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. provided by RefSeq, Jul 2008
Synonyms ABC20; CD243; CLCS; GP170; MDR1; p-170; P-GP; PGY1
Reference Data
Protein Categories CD Markers, Immune system diseases, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways ABC transporters
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Other "OTI5B3" antibodies (4)
SKU Description Size Price
CF801055 Carrier-free (BSA/glycerol-free) ABCB1 mouse monoclonal antibody, clone OTI5B3 (formerly 5B3) 100 ug
$620.00
TA801055 ABCB1 (P Glycoprotein) mouse monoclonal antibody, clone OTI5B3 (formerly 5B3) 100 ul
$447.00
TA801055AM ABCB1 mouse monoclonal antibody,clone 5B3, Biotinylated 100 ul
$509.00
TA801055BM ABCB1 mouse monoclonal antibody,clone 5B3, HRP conjugated 100 ul
$509.00

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