MAGEA3 Mouse Monoclonal Antibody [Clone ID: OTI2F10]

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TA800802
MAGEA3 mouse monoclonal antibody,clone OTI2F10
  $447.00
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Specifications
Specifications
Product Data
Clone Name OTI2F10
Application IHC, Simple Western, WB
Recommended Dilution WB 1:2000, IHC 1:150
Simple Western 1:100
Reactivity Human
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human MAGEA3 (NP_005353) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 34.6 kDa
Gene Name MAGE family member A3
Database Link
Background This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. provided by RefSeq, Jul 2008
Synonyms CT1.3; HIP8; HYPD; MAGE3; MAGEA6
Note WB application:Only overexpression results are guaranteed, not endogenous
Reference Data
Protein Categories Intracellular Proteins
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Other "OTI2F10" antibodies (6)
SKU Description Size Price
CF800802 Carrier-free (BSA/glycerol-free) MAGEA3 mouse monoclonal antibody,clone OTI2F10 100 ug
$620.00
TA600454 purified MAGEA3 mouse monoclonal capture antibody, validated for Luminex assays 100 ug
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TA700453 MAGEA3 biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays 50 ug
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TA800802AM MAGEA3 mouse monoclonal antibody,clone 2F10, Biotinylated 100 ul
$509.00
TA800802BM MAGEA3 mouse monoclonal antibody,clone 2F10, HRP conjugated 100 ul
$509.00
TA800802S MAGEA3 mouse monoclonal antibody,clone OTI2F10 30 ul
$200.00

file-alt Citations

Transcriptomic characterization of cancer-testis antigens identifies MAGEA3 as a driver of tumor progression in hepatocellular carcinoma
Craig, Garcia-Lezana, Ruiz de Galarreta et al
PLoS Genet (2021) 17 (6), e1009589 DOI: 10.1371/journal.pgen.1009589
Cited by 32
AI Summary: OriGene’s MAGEA3 (clone 1A10) antibody was used in this study to detect MAGEA3 protein expression, enabling the authors to assess its role in hepatocellular carcinoma progression.
Snippet: were transferred to a PVDF membrane for 2 hours at 60V (4°C). The membranes were probed using the following primary antibodies overnight at 4°C;GAPDH (clone 6C5, dilution 1:1,000) from EMD Millipore, MAGEA3 (clone 1A10, dilution 1:1,000) from Origene, TRIM28 Cached
WB
Cancer/testis Antigen MAGEA3 Interacts with STAT1 and Remodels the Tumor Microenvironment
Wang, Song, Zheng et al
Int J Med Sci (2018) 15 (14), 1702-1712 DOI: 10.7150/ijms.27643
Cited by 17
AI Summary: OriGene products contributed to this study by providing the MAGEA3-specific siRNA (OriGene, SR302279) used to silence MAGEA3 expression in tumor cells, enabling the investigation of its effects on STAT1 signaling and tumor microenvironment remodeling.
FigureFigureFigure
An aptamer targeting shared tumor-specific peptide antigen of MAGE-A3 in multiple cancers
Wang, Lin, Chen
Int. J. Cancer (2015)
Cited by 28
AI Summary: OriGene products, specifically the GFP-tagged human HLA cDNA clones HLA I (HLA-A1, Cat. No. RG200661) and HLA II (HLA-DRβ4, Cat. No. RG202743), were used for cell transfection to facilitate the study of aptamer binding to cancer cells in this research.
Snippet: Cell transfection. Green fluorescent protein (GFP)-tagged human HLA cDNA clones, HLA I (HLA-A1, Cat. No. RG200661) and HLA II (HLA-DRβ4, Cat. No. RG202743), in pCMV6-AC-GFP vector, were obtained from OriGene Technologies. ... Cite SaveSaving
FC IF
Showing 1-3 of 3 papers.
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