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ALK Mouse Monoclonal Antibody [Clone ID: OTI1E12]

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SKU
TA800730
ALK mouse monoclonal antibody, clone OTI1E12 (formerly 1E12)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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View other "ALK or NM_004304" antibodies

Specifications
Specifications
Product Data
Clone Name OTI1E12
Application IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human ALK (NP_004295) produced in HEK293T cell
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 176.3 kDa
Gene Name anaplastic lymphoma receptor tyrosine kinase
Database Link
Background This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X). provided by RefSeq, Jan 2011
Synonyms CD246; NBLST3
Reference Data
Protein Categories Cancer: Brain and CNS, Cancer: Haematopoietic and Lymphoid, Cancer: Lung, CD Markers, Enzyme: Kinases, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Protein Kinase
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Other "OTI1E12" antibodies (4)
SKU Description Size Price
CF800730 Carrier-free (BSA/glycerol-free) ALK mouse monoclonal antibody, clone OTI1E12 (formerly 1E12) 100 ug
$620.00
TA800730AM ALK mouse monoclonal antibody,clone 1E12, Biotinylated 100 ul
$509.00
TA800730BM ALK mouse monoclonal antibody,clone 1E12, HRP conjugated 100 ul
$509.00
TA800730S ALK mouse monoclonal antibody, clone OTI1E12 (formerly 1E12) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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